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Edratide

Product Name
Edratide
CAS No.
433922-67-9
Chemical Name
Edratide
Synonyms
Edratide;EDRATIDUM;Edratide [inn];Unii-38plp07bkc;Edratide Acetate;Glycyl-L-tyrosyl-L-tyrosyl-L-tryptophyl-L-seryl-L-tryptophyl-L-isoleucyl-L-arginyl-L-glutaminyl-L-prolyl-L-prolylglycyl-L-lysylglycyl-L-glutamyl-L-glutamyl-L-tryptophyl-L-isoleucylglycine;Glycine, glycyl-L-tyrosyl-L-tyrosyl-L-tryptophyl-L-seryl-L-tryptophyl-L-isoleucyl-L-arginyl-L-glutaminyl-L-prolyl-L-prolylglycyl-L-lysylglycyl-L-α-glutamyl-L-α-glutamyl-L-tryptophyl-L-isoleucyl-
CBNumber
CB91027205
Molecular Formula
C111H149N27O28
Formula Weight
2309.53
MOL File
433922-67-9.mol
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Edratide Property

Density 
1.50±0.1 g/cm3(Predicted)
form 
Solid
color 
White to off-white
Sequence
Gly-Tyr-Tyr-Trp-Ser-Trp-Ile-Arg-Gln-Pro-Pro-Gly-Lys-Gly-Glu-Glu-Trp-Ile-Gly
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0009369
Product name
TV-4710
Purity
95.00%
Packaging
5MG
Price
$499.28
Updated
2021/12/16
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Edratide Chemical Properties,Usage,Production

Uses

Treatment of systemic lupus erythematosus.

in vivo

Edratide (20-50 μg; s.c.; once a week for 10 weeks) exerts beneficial effects on SLE is through regulation of gene expression[2].
Edratide (50 μg/mouse; s.c.; 10 weekly) reduces the rates of apoptosis and down-regulates of caspase-8 and caspase-3, up-regulates Bcl-xL in SLE mouse[3].

Animal Model:6-7 months female mice (with established SLE)[2]
Dosage:20-50 μg
Administration:Subcutaneously injection; once a week for 10 weeks
Result:Up-regulated the RNA transcripts of Tnfsf4, Il5ra, Zbtb20, Nid1, down-regulated the transcripts of Tfpi and S100a8.
Animal Model:7-8 months SLE-afflicted BWF1 female mice[3]
Dosage:50 μg/mouse
Administration:S.c.; 10 weekly
Result:Reduced apoptosis, down-regulated caspase-8 and caspase-3, and up-regulated Bcl-xL.

Edratide Preparation Products And Raw materials

Raw materials

Preparation Products

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Edratide Suppliers

Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5501
Advantage
55
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 15951641583
Fax
025-58361106-806
Email
zhao.xu@njpeptide.com
Country
China
ProdList
9979
Advantage
55
Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4802
Advantage
58
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
7408
Advantage
58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
Advantage
58
Nanchang Tianzhen Biotechnology Co., Ltd
Tel
13758194781 13173652190
Email
522013271@qq.com
Country
China
ProdList
2395
Advantage
58
Wuhan Dingxintong Pharmaceutical Co. , Ltd.
Tel
+86-027-52344656 15871722230
Fax
2796190295
Email
15871722230@163.com
Country
China
ProdList
4684
Advantage
58
Hangzhou Go Top Peptide Biotech
Tel
15397062932
Email
sales1@gotopbio.com
Country
China
ProdList
3059
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
29668
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
13675144456
Email
alan.chow@synzest.com
Country
China
ProdList
9470
Advantage
58

433922-67-9, EdratideRelated Search:


  • Edratide
  • Edratide [inn]
  • Glycyl-L-tyrosyl-L-tyrosyl-L-tryptophyl-L-seryl-L-tryptophyl-L-isoleucyl-L-arginyl-L-glutaminyl-L-prolyl-L-prolylglycyl-L-lysylglycyl-L-glutamyl-L-glutamyl-L-tryptophyl-L-isoleucylglycine
  • Unii-38plp07bkc
  • EDRATIDUM
  • Edratide Acetate
  • Glycine, glycyl-L-tyrosyl-L-tyrosyl-L-tryptophyl-L-seryl-L-tryptophyl-L-isoleucyl-L-arginyl-L-glutaminyl-L-prolyl-L-prolylglycyl-L-lysylglycyl-L-α-glutamyl-L-α-glutamyl-L-tryptophyl-L-isoleucyl-
  • 433922-67-9
  • C111H149N27O28