ChemicalBook > CAS DataBase List > Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)

Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)

Product Name
Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)
CAS No.
645400-44-8
Chemical Name
Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)
Synonyms
tert-butyl ((1S,3S)-3-aminocyclopentyl)carbamate;tert-butyl N-[(1S,3S)-3-aminocyclopentyl]carbamate;[(1S,3S)-3-Amino-1-(boc-amino)cyclopentane;TERT-BUTYL ((IS, 3S)-3- AMINOCYCLOPENTYL)CARBAMATE;1,1-Dimethylethyl N-[(1S,3S)-3-aminocyclopentyl]carbamate;Carbamic acid, N-[(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester;Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)
CBNumber
CB91065960
Molecular Formula
C10H20N2O2
Formula Weight
200.28
MOL File
645400-44-8.mol
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Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) Property

Boiling point:
304.2±31.0 °C(Predicted)
Density 
1.04±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
12.37±0.40(Predicted)
InChI
InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-8-5-4-7(11)6-8/h7-8H,4-6,11H2,1-3H3,(H,12,13)/t7-,8-/m0/s1
InChIKey
PGBVMVTUWHCOHX-YUMQZZPRSA-N
SMILES
C(OC(C)(C)C)(=O)N[C@H]1CC[C@H](N)C1
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Safety

HS Code 
2924297099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
T205890
Product name
tert-Butyl((1S,3S)-3-Aminocyclopentyl)carbamate
Packaging
100mg
Price
$350
Updated
2021/12/16
AK Scientific
Product number
7526DF
Product name
Tert-Butyl((1S,3S)-3-aminocyclopentyl)carbamate
Packaging
5mg
Price
$158
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA158605
Product name
[(1S,3S)-3-Amino-1-(boc-amino)cyclopentane
Packaging
25mg
Price
$200
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA158605
Product name
[(1S,3S)-3-Amino-1-(boc-amino)cyclopentane
Packaging
50mg
Price
$300
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA158605
Product name
[(1S,3S)-3-Amino-1-(boc-amino)cyclopentane
Packaging
5mg
Price
$80
Updated
2021/12/16
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Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) Chemical Properties,Usage,Production

Uses

tert-butyl N-[(1S,3S)-3-aminocyclopentyl]carbamate is used as a reactant in the synthesis of C-2 hydroxyethyl imidazopyrrolo pyridines as JAK1 inhibitors.

Synthesis


A flask containing tert-butyl [(1S,3S)-3-aminocyclopentyl]carbamate (16.5 g, crude ~0.05 mol) and 1.7 g Pd-C (10% paste) in MeOH (300 mL) was exposed to a positive pressure of hydrogen gas (balloon) over weekend. The catalyst was filtered off and the mixture was concentrated to afford the title compound (9.5 g) as a thick colorless viscous oil. Tert-butyl [(1S,3S)-3-aminocyclopentyl]carbamate, Yield (9.5 g)

Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI) Suppliers

China 80 Europe 1 India 2 United Kingdom 1 United States 3 Global 87
Suzhou MgPlus Pharmtech Co., Ltd.
Tel
0512-66727658 18115508618
Email
phoenix888.ok@163.com
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China
ProdList
994
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Chengdu Feibai Pharmaceutical Co., Ltd.
Tel
028-84641798 18782128315
Email
3302391190@qq.com
Country
China
ProdList
9220
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55
Nanjing Becas pharmatech Ltd.
Tel
13912903754
Email
info@becaspharma.com
Country
China
ProdList
2427
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58
Nanjing Lebang Pharmaceutical Technology Co., Ltd
Tel
18860950986
Email
tangmanman@lebangpharma.com
Country
China
ProdList
566
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58
PharmaBlock Sciences (Nanjing), Inc.
Tel
4000255188 4000255188
Fax
025 86918232
Email
sales_china@pharmablock.com
Country
China
ProdList
9786
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58
Wuxi Kehua Biological Technology Co., Ltd.
Tel
0510-0510-86838766
Email
2258830676@qq.com
Country
China
ProdList
4589
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58
NANJING ZENJI PHARMACEUTICALS
Tel
025-58231105-8151
Fax
025-83172562
Email
marketing@zenjipharma.com
Country
China
ProdList
437
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Sichuan Tongsheng Amino acids Co.,Ltd.
Tel
0838-2809458 13350585791
Fax
+86-838-2274207
Email
pharm@biots.cn
Country
China
ProdList
333
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Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
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sales8178@energy-chemical.com
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China
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44688
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Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
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qq：2817624287
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lyh_antaeus@163.com
Country
China
ProdList
9347
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55

645400-44-8, Carbamic acid, [(1S,3S)-3-aminocyclopentyl]-, 1,1-dimethylethyl ester (9CI)Related Search:


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