ChemicalBook > CAS DataBase List > Pyridine, 2-bromo-5-(chloromethyl)- (9CI)

Pyridine, 2-bromo-5-(chloromethyl)- (9CI)

Product Name
Pyridine, 2-bromo-5-(chloromethyl)- (9CI)
CAS No.
168173-56-6
Chemical Name
Pyridine, 2-bromo-5-(chloromethyl)- (9CI)
Synonyms
2-BroMo-5-(chloroMethyl)pyridine;2-Fluoro-11-(methylthio)pyridine;Pyridine, 2-bromo-5-(chloromethyl)-;Pyridine, 2-bromo-5-(chloromethyl)- (9CI);7-(diethylamino)-3-(1,3-dimethylbenzimidazol-3-ium-2-yl)chromen-2-one,
CBNumber
CB91067979
Molecular Formula
C6H5BrClN
Formula Weight
206.47
MOL File
168173-56-6.mol
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Pyridine, 2-bromo-5-(chloromethyl)- (9CI) Property

Boiling point:
285.0±25.0 °C(Predicted)
Density 
1.631±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
0.02±0.10(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

aablocks
Product number
AA001XTL
Product name
2-Bromo-5-(chloromethyl)pyridine
Purity
96%
Packaging
250mg
Price
$118
Updated
2026/05/28
aablocks
Product number
AA001XTL
Product name
2-Bromo-5-(chloromethyl)pyridine
Purity
96%
Packaging
1g
Price
$285
Updated
2026/05/28
aablocks
Product number
AA001XTL
Product name
2-Bromo-5-(chloromethyl)pyridine
Purity
96%
Packaging
5g
Price
$840
Updated
2026/05/28
aablocks
Product number
AA001XTL
Product name
2-Bromo-5-(chloromethyl)pyridine
Purity
96%
Packaging
10g
Price
$1342
Updated
2026/05/28
aablocks
Product number
AA001XTL
Product name
2-Bromo-5-(chloromethyl)pyridine
Purity
96%
Packaging
25g
Price
$2509
Updated
2026/05/28
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Pyridine, 2-bromo-5-(chloromethyl)- (9CI) Chemical Properties,Usage,Production

Synthesis

122306-01-8

168173-56-6

General procedure for the synthesis of 2-bromo-5-(chloromethyl)pyridine from 2-bromo-5-(hydroxymethyl)pyridine: (6-bromopyridin-3-yl)methanol (1.000 g) was dissolved in dichloromethane (DCM, 10 mL) and cooled to 0°C. Thionyl chloride (1.260 g) was added slowly dropwise with stirring. After the dropwise addition was completed, the ice bath was removed and the reaction mixture was allowed to warm naturally to room temperature and stirring was continued for 2 hours. Upon completion of the reaction, the reaction solution was concentrated directly to give 1.050 g of 2-bromo-5-(chloromethyl)pyridine.

References

[1] Patent: WO2006/114213, 2006, A1. Location in patent: Page/Page column 30
[2] Patent: US5420270, 1995, A
[3] Journal of Medicinal Chemistry, 2012, vol. 55, # 7, p. 3201 - 3215
[4] Inorganic Chemistry, 2016, vol. 55, # 16, p. 7944 - 7953
[5] Journal of Biological Inorganic Chemistry, 2018, vol. 23, # 7, p. 1139 - 1151

Pyridine, 2-bromo-5-(chloromethyl)- (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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Pyridine, 2-bromo-5-(chloromethyl)- (9CI) Suppliers

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168173-56-6, Pyridine, 2-bromo-5-(chloromethyl)- (9CI)Related Search:


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  • 2-BroMo-5-(chloroMethyl)pyridine
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  • PYRIDINE