6-oxo-1,6-dihydropyridazine-4-carboxylicacid
- Product Name
- 6-oxo-1,6-dihydropyridazine-4-carboxylicacid
- CAS No.
- 867130-58-3
- Chemical Name
- 6-oxo-1,6-dihydropyridazine-4-carboxylicacid
- Synonyms
- 5-Carboxypyridazin-3(2H)-one;6-oxo-1H-pyridazine-4-carboxylic acid;6-Oxo-1,6-dihydro-4-pyridazinecarboxylic acid;1,6-Dihydro-6-oxopyridazine-4-carboxylic acid;1,6-dihydro-6-oxo-4-pyridazinecarboxylic acid;3-oxo-2,3-dihydropyridazine-5-carboxylic acid;1,6-Dihydro-6-oxo-pyridazin-4-carboxylic acid;4-Pyridazinecarboxylic acid, 1,6-dihydro-6-oxo-;1,6-Dihydro-6-oxopyridazine-4-carboxylic acid 95+%;6-oxo-1,6-dihydropyridazine-4-carboxylicacid ISO 9001：2015 REACH
- CBNumber
- CB91074012
- Molecular Formula
- C5H4N2O3
- Formula Weight
- 140.1
- MOL File
- 867130-58-3.mol
6-oxo-1,6-dihydropyridazine-4-carboxylicacid Property
- Melting point:
- 303 °C
- Density
- 1.63±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- pka
- 1.86±0.20(Predicted)
- Appearance
- Light brown to dark brown Solid
- InChI
- InChI=1S/C5H4N2O3/c8-4-1-3(5(9)10)2-6-7-4/h1-2H,(H,7,8)(H,9,10)
- InChIKey
- PSMIHCDKMNXTAY-UHFFFAOYSA-N
- SMILES
- C1=NNC(=O)C=C1C(O)=O
Safety
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- O855320
- Product name
- 6-Oxo-1,6-dihydropyridazine-4-carboxylicAcid
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 072955
- Product name
- 6-Oxo-1,6-dihydropyridazine-4-carboxylic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $258
- Updated
- 2021/12/16
- Product number
- W8905
- Product name
- 6-Oxo-1,6-dihydropyridazine-4-carboxylicacid
- Packaging
- 5g
- Price
- $438
- Updated
- 2021/12/16
- Product number
- 072955
- Product name
- 6-Oxo-1,6-dihydropyridazine-4-carboxylic acid
- Purity
- 95+%
- Packaging
- 5g
- Price
- $772
- Updated
- 2021/12/16
- Product number
- CHM0067466
- Product name
- 3-OXO-2,3-DIHYDROPYRIDAZINE-5-CARBOXYLIC ACID
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $831.6
- Updated
- 2021/12/16
6-oxo-1,6-dihydropyridazine-4-carboxylicacid Chemical Properties,Usage,Production
Synthesis
54709-94-3
867130-58-3
General procedure for the synthesis of 6-keto-1,6-dihydropyridazine-4-carboxylic acid from 5-methyl-3(2H)-pyridazinone: 5-methyl-3(2H)-pyridazinone (0.90 g, 8.2 mmol) was dissolved in concentrated sulfuric acid (13 mL), stirred and heated to 45 °C. Potassium permanganate (3.6 g, 12 mmol) was added in batches over a period of 30 min to control the reaction temperature to avoid a dramatic increase. After addition, the reaction was continued at 45°C with stirring for 30 minutes. After completion of the reaction, it was cooled to room temperature and quenched by adding ice water to the reaction mixture. The precipitate precipitated was collected by vacuum filtration and washed sequentially with cold water and ether to afford 0.98 g (87% yield) of the target product 6-keto-1,6-dihydropyridazine-4-carboxylic acid as a light green solid. The product was characterized by 1H NMR (300 MHz, CDCl3): δ 13.39 (broad single peak, 1H), 8.12 (single peak, 1H), 7.22 (single peak, 1H).
References
[1] Patent: US2007/259860, 2007, A1. Location in patent: Page/Page column 31-32
[2] Patent: WO2008/41075, 2008, A1. Location in patent: Page/Page column 55
[3] Patent: WO2008/41075, 2008, A1. Location in patent: Page/Page column 55
[4] Patent: US2007/259862, 2007, A1. Location in patent: Page/Page column 30
[5] Patent: US2009/111820, 2009, A1. Location in patent: Page/Page column 22
6-oxo-1,6-dihydropyridazine-4-carboxylicacid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-oxo-1,6-dihydropyridazine-4-carboxylicacid manufacturers
- Product
- 6-oxo-1,6-dihydropyridazine-4-carboxylicacid 867130-58-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-11-02
- Product
- 6-oxo-1,6-dihydropyridazine-4-carboxylicacid 867130-58-3
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2018-12-23
- Product
- 6-oxo-1,6-dihydropyridazine-4-carboxylicacid 867130-58-3
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2018-12-23