6-Iodoamiloride,hydrochloridedihydrate
- Product Name
- 6-Iodoamiloride,hydrochloridedihydrate
- CAS No.
- 60398-23-4
- Chemical Name
- 6-Iodoamiloride,hydrochloridedihydrate
- Synonyms
- 6-iodoamiloride;6-Iodoamiloride,HCldihydrate;3,5-Diamino-6-iodo-N-(aminoiminomethyl)pyrazine-2-carboxamide;2-Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-iodo-
- CBNumber
- CB91074744
- Molecular Formula
- C6H8IN7O
- Formula Weight
- 321.08
- MOL File
- 60398-23-4.mol
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- HCH0136000
- Product name
- 6-IODOAMILORIDE,HYDROCHLORIDEDIHYDRATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.78
- Updated
- 2021/12/16
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6-Iodoamiloride,hydrochloridedihydrate Chemical Properties,Usage,Production
Uses
6-Iodoamiloride is a potent acid-sensing ion channel 1 (ASIC1) inhibitor with an IC50 of 88 nM. 6-Iodoamiloride inhibits ASIC3-mediated currents from rat dorsal root ganglion neurons with an IC50 of 230 nM[1].
References
[1] Rocio K Finol-Urdaneta, et al. Automated Patch Clamp Screening of Amiloride and 5- N, N-Hexamethyleneamiloride Analogs Identifies 6-Iodoamiloride as a Potent Acid-Sensing Ion Channel Inhibitor. Mol Pharm. 2023 Jul 3;20(7):3367-3379. DOI:10.1021/acs.molpharmaceut.2c01083
6-Iodoamiloride,hydrochloridedihydrate Preparation Products And Raw materials
Raw materials
Preparation Products
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6-Iodoamiloride,hydrochloridedihydrate Suppliers
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 29423
- Advantage
- 58
- Tel
- +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19962
- Advantage
- 58
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