7-CHLOROIMIDAZO[1,2-A]PYRIDINE

Application

Product Name: 7-CHLOROIMIDAZO[1,2-A]PYRIDINE
CAS No.: 4532-25-6
Chemical Name: 7-CHLOROIMIDAZO[1,2-A]PYRIDINE
Synonyms: 7-CHLOROIMIDA;7-Chloroimidazo[1,2-a]pyr...;7-Chloroimdazo[1,2-A]pyridine;7-Chloroimidazo[1,2-a]pyridine;7-chloroimidazo[1,2-α]pyridine;IMidazo[1,2-a]pyridine, 7-chloro-;7-CHLOROIMIDAZO[1,2-A]PYRIDINE 98%
CBNumber: CB91091451
Molecular Formula: C7H5ClN2
Formula Weight: 152.58
MOL File: 4532-25-6.mol

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7-CHLOROIMIDAZO[1,2-A]PYRIDINE Property

Melting point:: 49-51 ºC
Density: 1.35
storage temp.: Inert atmosphere,Room Temperature
pka: 5.21±0.50(Predicted)
Appearance: Light yellow to brown Solid

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

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N-Bromosuccinimide Price

TRC

Product number: C368460
Product name: 7-Chloroimidazo[1,2-a]pyridine
Packaging: 500mg
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 068450
Product name: 7-Chloroimidazo[1,2-a]pyridine
Purity: >95%
Packaging: 1g
Price: $27
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-5-17
Product name: 7-Chloroimidazo[1,2-a]pyridine
Purity: 98%
Packaging: 1g
Price: $35
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC139447
Product name: 7-Chloroimidazo[1,2-a]pyridine
Packaging: 1g
Price: $50
Updated: 2021/12/16

Apolloscientific

Product number: OR110058
Product name: 7-Chloroimidazo[1,2-a]pyridine
Packaging: 1g
Price: $58
Updated: 2021/12/16

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7-CHLOROIMIDAZO[1,2-A]PYRIDINE Chemical Properties,Usage,Production

Application

7-Chloro-imidazolium pyridine is an imidazopyridine or pyrimidine derivative. Imidazolidine or pyrimidine derivatives are nitrogen-containing heterocyclic compounds fused with a five-membered imidazolium ring and a six-membered pyridine or pyrimidine ring. They are important pharmaceutical intermediates with wide applications in the fields of medicine, pesticides, and chemicals.

Synthesis

107-20-0

19798-80-2

4532-25-6

Synthesis of 7-chloroimidazo[1,2-a]pyridine (Compound 65-3) [0000229]: To an ethanol (15 mL) suspension of Compound 65-2 (HCl) was added sodium bicarbonate powder (3.3 g, 38.4 mmol, 4 eq.) and 50% aqueous chloroacetaldehyde (2.26 g, 14.4 mmol, 1.5 eq.). The reaction mixture was heated to reflux for 4 hours followed by stirring at room temperature for 16 hours. Upon completion of the reaction, the solvent was removed by concentration under reduced pressure. The residue was dissolved in water (10 mL) and ethyl acetate (10 mL) for liquid-liquid separation. The aqueous phase was further extracted with ethyl acetate (2 x 5 mL). All organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give compound 65-3 as a dark yellow oil (980 mg, 89% yield).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 3, p. 750 - 756
[2] Patent: WO2013/123215, 2013, A2. Location in patent: Paragraph 0000229
[3] Patent: EP2565185, 2013, A1. Location in patent: Paragraph 0114-0115
[4] European Journal of Medicinal Chemistry, 2015, vol. 94, p. 123 - 131
[5] Patent: WO2008/78100, 2008, A2. Location in patent: Page/Page column 93-94

7-CHLOROIMIDAZO[1,2-A]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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7-CHLOROIMIDAZO[1,2-A]PYRIDINE Suppliers

China 156 India 1 United Kingdom 2 United States 11 Global 170

Shangchem Co., Ltd.

Tel: +86-21-68182121
Fax: +86-21-68182121
Country: China
ProdList: 882
Advantage: 52

ChengDu TongChuangYuan Pharmaceutical Co.Ltd

Tel: 28-83379370 13880556291
Fax: 028-87747383
Email: tcy@tcypharm.com
Country: China
ProdList: 510
Advantage: 57

Pure Chemistry Scientific Inc.

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Fax: 001-617-206-9595
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Country: United States
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Advantage: 62

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Santai Labs, Inc.

Tel: 519-85601385
Fax: +86 519 8560 1389
Email: marketing@santailabs.com
Country: China
ProdList: 891
Advantage: 62

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

skychemical Co.Ltd

Tel: 021-20958197 20965099
Fax: 021-20960837
Email: sales@skychemical.com
Country: China
ProdList: 1183
Advantage: 57

SpringPharma Tech Co.,Ltd

Tel: +86-25-68710855, +86-25-68710897
Fax: 025-68710856
Email: sales@springpharma.net
Country: China
ProdList: 1261
Advantage: 62

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
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View Lastest Price from 7-CHLOROIMIDAZO[1,2-A]PYRIDINE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 7-CHLOROIMIDAZO[12-A]PYRIDINE 4532-25-6
Price: US $25.00-11.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200000KG
Release date: 2024-08-12

Career Henan Chemical Co

Product: 7-CHLOROIMIDAZO[1,2-A]PYRIDINE 4532-25-6
Price: US $1.00/kg
Min. Order: 1kg
Purity: 97%-99%
Supply Ability: as request
Release date: 2018-12-22

4532-25-6, 7-CHLOROIMIDAZO[1,2-A]PYRIDINERelated Search:

METHYL IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLATE methyl 3-bromoH-imidazo[1,2-a]pyridine-7-carboxylate 7-Fluoro-imidazo[1,2-a]pyridine 6-METHYLIMIDAZO[1,2-A]PYRIDINE 3-BROMO-7-METHYL-IMIDAZO[1,2-A]PYRIDINE Imidazo[1,2-a]pyridine-7-carboxylic acid (9CI) 3-BROMO-6-METHYLIMIDAZO[1,2-A]PYRIDINE 7-Nitroindole 7-hydroxy-7-phenylheptanoic acid(Seratrodast inteMediate) IMidazo[1,2-a]pyridine, 3,7-dibroMo- 7-CHLOROIMIDAZO[1,2-A]PYRIDINE 2,7-DICHLORO-IMIDAZO[1,2-A]PYRIDINE 2,6,7-TRICHLOROIMIDAZO[1,2-A]PYRIDINE 7-CHLORO-2-(4-CHLOROPHENYL)IMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE 2,6,7-TRICHLORO-3-IODOIMIDAZO[1,2-A]PYRIDINE 7-CHLORO-2-METHYL-IMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE 2-(4-BROMOPHENYL)-7-CHLOROIMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE 7-chloro-2-(chloromethyl)H-imidazo[1,2-a]pyridine

7-Chloroimdazo[1,2-A]pyridine

7-CHLOROIMIDAZO[1,2-A]PYRIDINE 98%

7-Chloroimidazo[1,2-a]pyridine

7-Chloroimidazo[1,2-a]pyr...

IMidazo[1,2-a]pyridine, 7-chloro-

7-chloroimidazo[1,2-α]pyridine

7-CHLOROIMIDA

4532-25-6

4532-25-3

Heterocycle-Pyridine series