ChemicalBook > CAS DataBase List > 6-Methoxybenzo(b)thiophene

6-Methoxybenzo(b)thiophene

Product Name
6-Methoxybenzo(b)thiophene
CAS No.
90560-10-4
Chemical Name
6-Methoxybenzo(b)thiophene
Synonyms
6-Methoxybenzothiophene;6-Methoxybenzo(b)thiophene;6-methoxy-1-benzothiophene;Benzo[b]thiophene, 6-Methoxy-;1-benzothiophen-6-yl methyl ether;6-Methoxybenzo(b)thiophene ISO 9001：2015 REACH
CBNumber
CB91103174
Molecular Formula
C9H8OS
Formula Weight
164.22
MOL File
Mol file
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6-Methoxybenzo(b)thiophene Property

Melting point:
38-39 °C
Boiling point:
153-156 °C(Press: 16 Torr)
Density 
1.198±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
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Safety

HS Code 
2932990090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
M223250
Product name
6-Methoxybenzo[B]thiophene
Packaging
50mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
5075AC
Product name
6-Methoxybenzo[b]thiophene
Packaging
1g
Price
$294
Updated
2021/12/16
Matrix Scientific
Product number
153862
Product name
6-Methoxybenzo[b]thiophene
Purity
95%
Packaging
1g
Price
$315
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0391394
Product name
6-METHOXYBENZO[B]THIOPHENE
Purity
95.00%
Packaging
5MG
Price
$497.85
Updated
2021/12/16
Matrix Scientific
Product number
153862
Product name
6-Methoxybenzo[b]thiophene
Purity
95%
Packaging
5g
Price
$885
Updated
2021/12/16
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6-Methoxybenzo(b)thiophene Chemical Properties,Usage,Production

Description

6-Methoxybenzo(b)thiophene is a derivative of benzo[b]thiophene. The benzo[b]thiophene scaffold holds a pivotal place as a pharmacophore for the development of anticancer agents. In addition, this scaffold has many pharmacological activities[1].

Synthesis

A solution of the crude 1- (2, 2-diethoxyethylsulfanyl)-3-methoxybenzene (8.27 g, 32.3 mmol) in hexane (100 ml) was added dropwise to a solution of methanesulfonic acid (1.05 mL, 1.55 g, 16.1 mmol) in hexane (1000 mL) containing 16.5 g of celite (2 wt. eq.). The resultant solution was heated at reflux for 1 hour. After cooling to room temperature, the reaction was quenched by the addition of Et3N (4.5 ml, 3.26 g, 32.3 mmol. The crude reaction mixture was filtered and then concentrated in vacuo. 6-Methoxybenzo(b)thiophene was obtained after purification.

References

[1] Romagnoli R, et al. Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents. Bioorganic Chemistry, 2021.

6-Methoxybenzo(b)thiophene Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-Methoxybenzo(b)thiophene manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
6-Methoxybenzo(b)thiophene 90560-10-4
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-04-27
Career Henan Chemical Co
Product
6-Methoxybenzo(b)thiophene 90560-10-4
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/T
Release date
2019-12-24

90560-10-4, 6-Methoxybenzo(b)thiopheneRelated Search:

6-METHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID 6-METHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER

  • 6-Methoxybenzo(b)thiophene
  • 6-Methoxybenzothiophene
  • Benzo[b]thiophene, 6-Methoxy-
  • 6-methoxy-1-benzothiophene
  • 6-Methoxybenzo(b)thiophene ISO 9001：2015 REACH
  • 1-benzothiophen-6-yl methyl ether
  • 90560-10-4