3-FLUORO-5-FORMYL-2-METHOXYPYRIDINE

Product Name: 3-FLUORO-5-FORMYL-2-METHOXYPYRIDINE
CAS No.: 884494-73-9
Chemical Name: 3-FLUORO-5-FORMYL-2-METHOXYPYRIDINE
Synonyms: 3-FLUORO-5-FORMYL-2-METHOXYPYRIDINE;5-FLUORO-6-METHOXY-PYRIDINE-3-CARBALDEHYDE;5-Fluoro-6-methoxy-3-pyridinecarboxaldehyde;3-Pyridinecarboxaldehyde, 5-fluoro-6-methoxy-;5-fluoro-6-methoxypyridine-3-carbaldehyde - [F87722]
CBNumber: CB9111350
Molecular Formula: C7H6FNO2
Formula Weight: 155.13
MOL File: Mol file

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3-FLUORO-5-FORMYL-2-METHOXYPYRIDINE Property

Boiling point:: 236.0±35.0 °C(Predicted)
Density: 1.266±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -0.82±0.20(Predicted)
Appearance: White to off-white Solid

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Safety

Hazard Codes: Xn
Risk Statements: 22
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Apolloscientific

Product number: PC201349
Product name: 5-Fluoro-6-methoxynicotinaldehyde
Purity: 98%
Packaging: 250mg
Price: $128
Updated: 2021/12/16

Apolloscientific

Product number: PC201349
Product name: 5-Fluoro-6-methoxynicotinaldehyde
Purity: 98%
Packaging: 1g
Price: $301
Updated: 2021/12/16

Matrix Scientific

Product number: 119595
Product name: 5-Fluoro-6-methoxynicotinaldehyde
Purity: 95+%
Packaging: 250mg
Price: $490
Updated: 2021/12/16

Matrix Scientific

Product number: 119595
Product name: 5-Fluoro-6-methoxynicotinaldehyde
Purity: 95+%
Packaging: 1g
Price: $1224
Updated: 2021/12/16

AK Scientific

Product number: Z5255
Product name: 5-Fluoro-6-methoxynicotinaldehyde
Packaging: 1g
Price: $1702
Updated: 2021/12/16

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3-FLUORO-5-FORMYL-2-METHOXYPYRIDINE Chemical Properties,Usage,Production

Synthesis

959616-65-0

884494-73-9

Dess-Martin periodinane (DMP, 27.37 g, 64.4 mmol) was added batchwise to a stirred solution of (5-fluoro-6-methoxypyridin-3-yl)methanol (6.8 g, 43.83 mmol) in dichloromethane (DCM, 150 mL) at 0 °C. The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the reaction mixture was filtered through diatomaceous earth and washed with DCM (3 x 50 mL). The combined organic phases were washed sequentially with saturated aqueous NaHCO3 solution (200 mL), water (100 mL) and brine (150 mL), dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure to give the crude product. The crude product was purified by column chromatography (silica gel 60-120 mesh, 0-15% petroleum ether solution of ethyl acetate) to obtain 5-fluoro-6-methoxynicotinaldehyde (6.0 g, 89% yield) as a white solid.

References

[1] Patent: EP2022793, 2009, A1. Location in patent: Page/Page column 73
[2] Patent: WO2015/158427, 2015, A1. Location in patent: Page/Page column 85
[3] Patent: EP2022793, 2009, A1. Location in patent: Page/Page column 73

3-FLUORO-5-FORMYL-2-METHOXYPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-FLUORO-5-FORMYL-2-METHOXYPYRIDINE Suppliers

China 52 India 2 United States 8 Global 62

Shanghai yirong biology science and technology co., ltd

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884494-73-9, 3-FLUORO-5-FORMYL-2-METHOXYPYRIDINERelated Search:

5-FLUORO-6-METHOXY-PYRIDINE-3-CARBALDEHYDE

3-FLUORO-5-FORMYL-2-METHOXYPYRIDINE

5-Fluoro-6-methoxy-3-pyridinecarboxaldehyde

3-Pyridinecarboxaldehyde, 5-fluoro-6-methoxy-

5-fluoro-6-methoxypyridine-3-carbaldehyde - [F87722]

884494-73-9