ChemicalBook > CAS DataBase List > Gly-Met-Ala-Ser-Lys-Ala-Gly-Ala-Ile-Ala-Gly-Lys-Ile-Ala-Lys-Val-Ala-Leu-Lys-Ala-Leu-NH2
Gly-Met-Ala-Ser-Lys-Ala-Gly-Ala-Ile-Ala-Gly-Lys-Ile-Ala-Lys-Val-Ala-Leu-Lys-Ala-Leu-NH2
- Product Name
- Gly-Met-Ala-Ser-Lys-Ala-Gly-Ala-Ile-Ala-Gly-Lys-Ile-Ala-Lys-Val-Ala-Leu-Lys-Ala-Leu-NH2
- CAS No.
- 102068-15-5
- Chemical Name
- Gly-Met-Ala-Ser-Lys-Ala-Gly-Ala-Ile-Ala-Gly-Lys-Ile-Ala-Lys-Val-Ala-Leu-Lys-Ala-Leu-NH2
- Synonyms
- MSI 499;peptide-Gly-Leu-amide;PGLa ion channel-forming peptide;741: PN: US20050058603 SEQID: 736 claimed protein;L-Leucinamide,glycyl-L-methionyl-L-alanyl-L-seryl-L-lysyl-L-alanylglycyl-L-alanyl-L-isoleucyl-L-alanylglycyl-L-lysyl-L-isoleucyl-L-alanyl-L-lysyl-L-valyl-L-alanyl-L-leucyl-L-lysyl-L-alanyl-
- CBNumber
- CB91118374
- Molecular Formula
- C88H162N26O22S
- Formula Weight
- 1968.45
- MOL File
- 102068-15-5.mol
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Gly-Met-Ala-Ser-Lys-Ala-Gly-Ala-Ile-Ala-Gly-Lys-Ile-Ala-Lys-Val-Ala-Leu-Lys-Ala-Leu-NH2 Property
- storage temp.
- Sealed in dry,2-8°C
- solubility
- H2O: soluble1mg/mL
- form
- solid
- Water Solubility
- H2O: 1mg/mL
- Sequence
- Gly-Met-Ala-Ser-Lys-Ala-Gly-Ala-Ile-Ala-Gly-Lys-Ile-Ala-Lys-Val-Ala-Leu-Lys-Ala-Leu-NH2
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Safety
- WGK Germany
- 2
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- P0053
- Product name
- PGLa
- Packaging
- 500μg
- Price
- $366
- Updated
- 2023/01/07
American Custom Chemicals Corporation
- Product number
- PEP0002842
- Product name
- GLY-MET-ALA-SER-LYS-ALA-GLY-ALA-ILE-ALA-GLY-LYS-ILE-ALA-LYS-VAL-ALA-LEU-LYS-ALA-LEU-NH2
- Purity
- 95.00%
- Packaging
- 0.5MG
- Price
- $658.35
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- PEP0002842
- Product name
- GLY-MET-ALA-SER-LYS-ALA-GLY-ALA-ILE-ALA-GLY-LYS-ILE-ALA-LYS-VAL-ALA-LEU-LYS-ALA-LEU-NH2
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $794.36
- Updated
- 2021/12/16
Crysdot
- Product number
- CD22005274
- Product name
- Gly-Met-Ala-Ser-Lys-Ala-Gly-Ala-Ile-Ala-Gly-Lys-Ile-Ala-Lys-Val-Ala-Leu-Lys-Ala-Leu-NH2
- Purity
- 95+%
- Packaging
- 5mg
- Price
- $594
- Updated
- 2021/12/16
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Gly-Met-Ala-Ser-Lys-Ala-Gly-Ala-Ile-Ala-Gly-Lys-Ile-Ala-Lys-Val-Ala-Leu-Lys-Ala-Leu-NH2 Chemical Properties,Usage,Production
Uses
PGLa is a cationic antimicrobial peptide (AMP) originally isolated from frog. It has been shown to have antibacterial,1 antifungal,2 and antiviral,3 activities. It is used to study novel peptide fragments th at originate from PGLa and multinucleated gastric mucosal cells of Xenopus laevis.
Biological Activity
The precursors of PGLa are caerulein and xenopsin. The mechanism of action of PGLa against Gram-negative bacteria is disruption of the cellular lipid bilayer.4 It is used to induce transmembrane pore formation in lipid bilayers and bacterial cell membranes. It is used in combination with magainin 2 for a synergistic effect.
Gly-Met-Ala-Ser-Lys-Ala-Gly-Ala-Ile-Ala-Gly-Lys-Ile-Ala-Lys-Val-Ala-Leu-Lys-Ala-Leu-NH2 Preparation Products And Raw materials
Raw materials
Preparation Products
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