ChemicalBook > CAS DataBase List > T-BUTYL 4-BROMOBUTYRATE

T-BUTYL 4-BROMOBUTYRATE

Product Name: T-BUTYL 4-BROMOBUTYRATE
CAS No.: 110661-91-1
Chemical Name: T-BUTYL 4-BROMOBUTYRATE
Synonyms: Elagolix Impurity 12;Elagolix Impurity 32;ert-Butyl4-bromobutanoate;tert-Butyl4-bromobutanoate95%;tert-Butyl 4-bromobutanoate, tech;1,1-Dimethylethyl 4-bromobutanoate;4-Bromobutanoic acid tert-butyl ester;110661-91-1;Butanoic acid, 4-broMo-,1,1-diMethylethyl ester;tert-Butyl 4-bromobutanoate , tert-Butyl 4-bromobutanoate
CBNumber: CB91118864
Molecular Formula: C8H15BrO2
Formula Weight: 223.11
MOL File: 110661-91-1.mol

Less

T-BUTYL 4-BROMOBUTYRATE Property

Boiling point:: 225.9±23.0 °C(Predicted)
Density: 1.258±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
solubility: soluble in Chloroform, Hexane
form: liquid
color: Colourless to light yellow

Less

Safety

Risk Statements: 34-36/37/38
Safety Statements: 22-26-36/37/39-45
RIDADR: 1760
HazardClass: 8
PackingGroup: Ⅲ
HS Code: 29033990

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: B6167
Product name: tert-Butyl 4-Bromobutanoate
Purity: min. 97.0 %
Packaging: 5G
Price: $93
Updated: 2025/07/31

TCI Chemical

Product number: B6167
Product name: tert-Butyl 4-Bromobutanoate
Purity: min. 97.0 %
Packaging: 25G
Price: $369
Updated: 2025/07/31

TRC

Product number: B682040
Product name: t-Butyl4-Bromobutyrate
Packaging: 1g
Price: $130
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB140514
Product name: tert-Butyl 4-bromobutanoate
Packaging: 5G
Price: $150
Updated: 2021/12/16

Matrix Scientific

Product number: 113978
Product name: tert-Butyl 4-bromobutanoate
Purity: 97%
Packaging: 25g
Price: $168
Updated: 2021/12/16

Less

T-BUTYL 4-BROMOBUTYRATE Chemical Properties,Usage,Production

Uses

t-Butyl 4-Bromobutyrate. is a potent CB1 receptor antagonist involved in the cannabinoid-1 receptor signalling process. Inhibition of this receptor has been demonstrated to inhibit feeding behaviors. Antiinflammatory.

Synthesis

2623-87-2

75-65-0

110661-91-1

The general procedure for the synthesis of tert-butyl 4-bromobutyrate from 4-bromobutyric acid and tert-butanol was as follows: 4-bromobutyric acid (2.57 g, 15.39 mmol, 1 eq.) was dissolved in dichloromethane (20 mL), magnesium sulfate (7.74 g, 64.30 mmol, 4.2 eq.), tert-butanol (5.70 g, 76.95 mmol, 5 eq.) and concentrated sulfuric acid (0.25 mL). The reaction mixture was stirred at room temperature for 2 days. Upon completion of the reaction, the reaction was quenched by the addition of saturated aqueous sodium bicarbonate and the reaction mixture was extracted with dichloromethane. The organic layers were combined, washed with saturated sodium chloride solution and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give the crude product. The crude product was purified by medium pressure silica gel column chromatography (eluent: n-hexane/ethyl acetate=50/50) to afford the target compound tert-butyl 4-bromobutyrate (1.17 g, 5.24 mmol, 47% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3) and 13C NMR (100 MHz, CDCl3): 1H NMR δ 1.27 (s, 9H), 1.91-1.98 (m, 2H), 2.22 (t, 2H, J=7.2Hz), 3.27 (t, 2H, J=6.5Hz); 13C NMR δ 27.9 , 28.0, 32.8, 33.7, 80.5, 171.7.

References

[1] Tetrahedron Asymmetry, 2004, vol. 15, # 8, p. 1247 - 1258
[2] ACS Combinatorial Science, 2016, vol. 18, # 12, p. 710 - 722
[3] Angewandte Chemie - International Edition, 2010, vol. 49, # 15, p. 2738 - 2742
[4] European Journal of Organic Chemistry, 2003, # 8, p. 1486 - 1493
[5] Patent: US2018/52109, 2018, A1. Location in patent: Paragraph 0156; 0157; 0158; 0159

T-BUTYL 4-BROMOBUTYRATE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

T-BUTYL 4-BROMOBUTYRATE Suppliers

Americas 1 Canada 1 China 137 Europe 1 India 4 Japan 1 United Kingdom 3 United States 9 Global 157

Hangzhou Aiken New Materials Co., Ltd

Tel: 15258847994 15258847994
Email: 1624352@qq.com
Country: China
ProdList: 248
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16075
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

AllyChem Co., Ltd.

Tel: 0411-62313318 13942603642
Fax: 0411-87549748
Email: info@allychem.com
Country: China
ProdList: 1028
Advantage: 65

Nanjing Credit Trading Co.,Ltd

Tel: 025-52164950
Fax: 025-86800069
Email: Googlexu_0114@sina.com
Country: China
ProdList: 644
Advantage: 58

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883
Fax: 0731-82251112
Email: sales@huatengsci.com
Country: China
ProdList: 5872
Advantage: 58

Mashilabs (Shanghai) Co.,Ltd.

Tel: 19916721580
Fax: QQ：3154870176
Email: mafarm@126.com
Country: China
ProdList: 4542
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
Advantage: 55

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

Nanjing Chalf-Pharm Technology Co., Ltd.

Tel: 025-57018978 18251899859
Fax: 025-57018008
Email: sales@chalf-pharm.com
Country: China
ProdList: 5674
Advantage: 50

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Quzhou Rundong Chemical (Technology) Co.

Tel: 0570-8789886 18892685668
Fax: 0570-8789985
Email: info@rundongchemical.com
Country: China
ProdList: 4053
Advantage: 60

SanoChem (Chengdu) Tech. Co., Ltd.

Tel: 28-87999436 02887999436
Fax: QQ:2746983436
Email: sales@sano-chem.com
Country: China
ProdList: 3795
Advantage: 55

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 021-58088081 Q2635253576
Fax: QQ3382968513
Email: hailey@shsendpharm.com
Country: China
ProdList: 2081
Advantage: 55

Hubei Chuangliankangcheng Pharmaceutical Co., Ltd.

Tel: 027-65388397 18164111589
Fax: 027-65388397
Email: 3321478047@qq.com
Country: China
ProdList: 2007
Advantage: 55

Haimen Ruiyi Medical Tech Co., LTD

Tel: 021-54718086
Fax: 021-54711707
Email: sales5@ruiyitech.com
Country: China
ProdList: 271
Advantage: 58

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9627
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Suzhou JingTong Pharmaceutical Co., Ltd.

Tel: 13675155016
Fax: 18912765016
Email: tongtf110@sina.com
Country: China
ProdList: 963
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Kangman Biological Technology Co., Ltd.

Tel: 18800375331
Fax: 021-50908862
Email: kangmansales@163.com
Country: China
ProdList: 7570
Advantage: 55

Taian Jiaye Biotechnology Co.Ltd

Tel: 13127280945
Email: 285424065@qq.com
Country: China
ProdList: 9976
Advantage: 55

Wuhan EEChem Technologies Co., Ltd

Tel: 0711-3617768 13308685235
Fax: 0711-3616558
Email: lihongcai4360@sina.com
Country: China
ProdList: 1510
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28785
Advantage: 58

Hangzhou Molcore Biopharmatech Co.,Ltd

Tel: 400-711-5280 86-571-81025280
Fax: 86-571-85806285
Email: sales@molcore.com
Country: China
ProdList: 9967
Advantage: 58

Jiaxing Deyi Chemical Co., Ltd.

Tel: 86-0573-85866609 13325730825
Fax: 0573-85866609
Email: 945717149@qq.com
Country: China
ProdList: 8596
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15083
Advantage: 58

Suzhou Nuoouman Biological Technology Co., Ltd.

Tel: 15026866316
Email: 180642609@qq.com
Country: China
ProdList: 4967
Advantage: 58

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6039 18920764717
Email: sales@heowns.com
Country: China
ProdList: 23771
Advantage: 60

Jinan Kabotang Biological Technology Co.,Ltd.

Tel: 0531-61320525 15866703830
Email: figo.gao@foxmail.com
Country: China
ProdList: 5178
Advantage: 58

Shanghai SPAR pharmaceutical technology co., LTD

Tel: 021-000000 13917643586;
Email: admin@jingshipharmatech.com
Country: China
ProdList: 9856
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-63315541 13323832564
Fax: QQ:3001332135
Email: 3001332135@qq.com
Country: China
ProdList: 9972
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shanghai Moss Medicine Technology Co., Ltd.

Tel: +86-188369842 +86-15618151133
Fax: QQ188369842
Email: 188369842@qq.com
Country: China
ProdList: 1959
Advantage: 58

Guangdong wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2815688 13927872512
Fax: 0751-8963795
Email: 3007421951@qq.com
Country: China
ProdList: 9939
Advantage: 58

Beijing Minruida Technology Co., Ltd.

Tel: 010-82387566 18001021521;
Fax: 82387566-801
Email: sales@mreda.com.cn
Country: China
ProdList: 10083
Advantage: 58

Suzhou Rovathin Foreign Trade Co.,Ltd

Tel: 0512-65816829 18662214788
Fax: 0512-65816829
Email: info@rovathin.com.cn
Country: China
ProdList: 9987
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-55055611 18137792234
Fax: QQ：3002694073
Email: 3002694073@qq.com
Country: China
ProdList: 9987
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

Less

View Lastest Price from T-BUTYL 4-BROMOBUTYRATE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: T-BUTYL 4-BROMOBUTYRATE 110661-91-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-15

Career Henan Chemical Co

Product: T-BUTYL 4-BROMOBUTYRATE 110661-91-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-07-03

110661-91-1, T-BUTYL 4-BROMOBUTYRATE Related Search:

Carbamic acid, N-[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]-, 1,1-dimethylethyl ester 1-[(1R)-2-hydroxy-1-phenylethyl]pyrrolidin-2-one (R)-2-(Boc-aMino)-2-phenylethyl 4-Methylbenzenesulfonate 3-Bromo-2-fluoroanisole 1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione 1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA elagolix (R)-1,2-Diamino-1-phenylethane Elagolix Sodium impurity4 2,2'-difluoro-3,3'-dimethoxy-1,1'-biphenyl 5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione 3-[(2R)-2-Amino-2-phenylethyl]-5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione 5-(2-Fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione 4-Bromobutyl acetate Carbamic acid, N-[(1R)-2-[5-bromo-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]-, 1,1-dimethylethyl ester Carbamic acid, N-[(1R)-2-[5-(2-fluoro-3-hydroxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]-, 1,1-dimethylethyl ester 2,4(1H,3H)-Pyrimidinedione, 3-[(2R)-2-amino-2-phenylethyl]-5-(2-fluoro-3-hydroxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl- O-Demethyl elagolix sodium

Butanoic acid, 4-broMo-,1,1-diMethylethyl ester

tert-Butyl 4-bromobutanoate, tech

tert-Butyl4-bromobutanoate95%

4-Bromobutanoic acid tert-butyl ester

Elagolix Impurity 32

Elagolix Impurity 12

ert-Butyl4-bromobutanoate

1,1-Dimethylethyl 4-bromobutanoate

tert-Butyl 4-bromobutanoate , tert-Butyl 4-bromobutanoate

110661-91-1

Acids & Esters

Bromine Compounds