Pradimicin A
- Product Name
- Pradimicin A
- CAS No.
- 117704-65-1
- Chemical Name
- Pradimicin A
- Synonyms
- Pradimicin A;D-Alanine, N-[[(5S,6S)-5-[[4,6-dideoxy-4-(methylamino)-3-O-β-D-xylopyranosyl-β-D-galactopyranosyl]oxy]-5,6,8,13-tetrahydro-1,6,9,14-tetrahydroxy-11-methoxy-3-methyl-8,13-dioxobenzo[a]naphthacen-2-yl]carbonyl]-
- CBNumber
- CB91120654
- Molecular Formula
- C40H44N2O18
- Formula Weight
- 840.784
- MOL File
- 117704-65-1.mol
Pradimicin A Property
- Melting point:
- 193-195 °C (decomp)
- Boiling point:
- 1120.3±65.0 °C(Predicted)
- Density
- 1.68±0.1 g/cm3(Predicted)
- pka
- 2.99±0.10(Predicted)
N-Bromosuccinimide Price
- Product number
- API0012307
- Product name
- PRADIMICIN A
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.55
- Updated
- 2021/12/16
Pradimicin A Chemical Properties,Usage,Production
Uses
Pradimicin A (PRM-A) is a potent antifungal agent, with an MIC of 4 μg/mL against Candida rugosa. Pradimicin A has antiviral activities against CoV, HIV and other enveloped viruses. Pradimicin A shows aggregation property, and can recognize d-Man in the presence of Ca2+ ion[1][2].
Definition
ChEBI: A member of the class of pradimicins that is isolated from the cultured broth of Actinomadura hibisca No. P157-2 (ATCC 53557).
References
[1] Miyanishi W, et al. d-Mannose binding, aggregation property, and antifungal activity of amide derivatives of pradimicin A. Bioorg Med Chem. 2021 Dec 27;55:116590. DOI:10.1016/j.bmc.2021.116590
[2] Nakagawa Y, Doi T, Masuda Y, Takegoshi K, Igarashi Y, Ito Y. Mapping of the primary mannose binding site of pradimicin A. J Am Chem Soc. 2011 Nov 2;133(43):17485-93. DOI:10.1021/ja207816h
Pradimicin A Preparation Products And Raw materials
Raw materials
Preparation Products
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