3'-DEPHOSPHOCOENZYME A

Product Name
3'-DEPHOSPHOCOENZYME A
CAS No.
3633-59-8
Chemical Name
3'-DEPHOSPHOCOENZYME A
Synonyms
Dephospho-CoA;3'-dephospho-CoA;dephosphocoenzyme A;3'-DEPHOSPHOCOENZYME A;3'-Dephosphocoenzyme A;3'-O-dephosphono-coenzyme A;Coenzyme A, 3'-O-dephosphono-;3'-DEPHOSPHOCOENZYME A FREE ACID;3'-Dephosphocoenzyme A >=90% (HPLC);[5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[hydroxy-[3-hydroxy-2,2-dimethyl-3-[2-(2-sulfanylethylcarbamoyl)ethylcarbamoyl]propoxy]-phosphoryl]oxy-phosphinic acid
CBNumber
CB9115282
Molecular Formula
C21H35N7O13P2S
Formula Weight
687.55
MOL File
3633-59-8.mol
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3'-DEPHOSPHOCOENZYME A Property

Density 
1.85±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Water: 50 mg/ml
form 
A crystalline solid
pka
1.16±0.50(Predicted)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D3385
Product name
3′-Dephosphocoenzyme A
Purity
≥90% (HPLC)
Packaging
5mg
Price
$218
Updated
2024/03/01
Sigma-Aldrich
Product number
D3385
Product name
3′-Dephosphocoenzyme A
Purity
≥90% (HPLC)
Packaging
25mg
Price
$782
Updated
2024/03/01
Cayman Chemical
Product number
27390
Product name
3''-Dephosphocoenzyme A
Packaging
1mg
Price
$60
Updated
2024/03/01
Cayman Chemical
Product number
27390
Product name
3''-Dephosphocoenzyme A
Packaging
10mg
Price
$351
Updated
2024/03/01
Cayman Chemical
Product number
27390
Product name
3''-Dephosphocoenzyme A
Packaging
5mg
Price
$190
Updated
2024/03/01
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3'-DEPHOSPHOCOENZYME A Chemical Properties,Usage,Production

Description

3''-Dephosphocoenzyme A is an intermediate in the biosynthesis of coenzyme A (CoA; Item Nos. 16147 | 21499 | 21722) from pantothenic acid (vitamin B5; ). It is phosphorylated by CoA synthase in humans to form CoA. 3''-Dephosphocoenzyme A can be used as a transcription initiator in the synthesis of CoA-RNA by in vitro transcription.

Uses

Dephosphocoenzyme A is the direct precursor of coenzyme A. It is used for the synthesis of coenzyme A by bifunctional CoA Synthase (CoASy, 4′-phosphopantetheine adenylyltransferase/dephospho-CoA kinase) which performs the transfer of the γ-phosphate of ATP to dephosphocoenzyme A.

Definition

ChEBI: An adenosine 5'-phosphate that is coenzyme A in which the phosphate group at position 3' has been replaced by a hydrogen atom. It is an intermediate metabolite in pantothenate and CoA biosynthesis

Biochem/physiol Actions

3′-Dephosphocoenzyme A (DepCoA), also called desphosphoCoA (dpCoA), is synthesized from 4-phosphopantetheine by the enzyme phosphopanthetheine adenylyltransferase. It is an intermediate in coenzyme A biosynthetic pathway. In the presence of dephospho-CoA kinase (CoaE), dephosphocoenzyme A is converted to coenzyme A. 3′-Dephosphocoenzyme shares adenosine-diphosphate substructure as like the purines and is a non-canonical nucleotide and is an initiator of transcription initiation. It is routinely used in in vitro transcription studies to initiate RNA synthesis.

3'-DEPHOSPHOCOENZYME A Preparation Products And Raw materials

Raw materials

Preparation Products

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3'-DEPHOSPHOCOENZYME A Suppliers

China 16 Switzerland 1 United Kingdom 1 United States 5 Global 23
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
NewCan Biotech Limited
Tel
+86-0571-86912261 +8613735419629
Email
sales@newcanbio.com
Country
China
ProdList
9980
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Changzhou Furuisi Biotechnology Co., Ltd
Tel
0519-85524369
Email
3477467573@qq.com
Country
China
ProdList
8617
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58

3633-59-8, 3'-DEPHOSPHOCOENZYME ARelated Search:

COENZYME A TRILITHIUM SALT MYRISTOYL COENZYME A C14:0 LITHIUM SALT COENZYME A TRILITHIUM SALT DIHYDRATE ACETYL COENZYME A (C2:0) LITHIUM LAUROYL COENZYME A C12:0 LITHIUM SALT ACETOACETYL COENZYME A, TETRALITHIUM PENTAHYDRATE LITHIUM SALT C4:0 N-OCTADECANOYL COENZYME A LITHIUM SALT ACETOACETYL COENZYME A LITHIUM SALT CIS-9-OCTADECENOYL COENZYME A LITHIUM SALT CAPROYL COENZYME A TRILITHIUM SALT METHYLMALONYL COENZYME A LITHIUM 3'-DEPHOSPHOCOENZYME A LINOLEOYL COENZYME A (C18:2) LITHIUM SALT

  • 3'-DEPHOSPHOCOENZYME A
  • 3'-DEPHOSPHOCOENZYME A FREE ACID
  • [5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[hydroxy-[3-hydroxy-2,2-dimethyl-3-[2-(2-sulfanylethylcarbamoyl)ethylcarbamoyl]propoxy]-phosphoryl]oxy-phosphinic acid
  • Dephospho-CoA
  • dephosphocoenzyme A
  • 3'-dephospho-CoA
  • Coenzyme A, 3'-O-dephosphono-
  • 3'-Dephosphocoenzyme A >=90% (HPLC)
  • 3'-O-dephosphono-coenzyme A
  • 3'-Dephosphocoenzyme A
  • 3633-59-8
  • C21H33N7O13P2S2Li
  • C21H35N7O13P2S
  • BioChemical
  • Lipid Library
  • Metabolomics
  • Metabolic Libraries
  • Acyl Transfer ReagentsMetabolic Pathways
  • Lipid LibraryMetabolites and Cofactors on the Metabolic Pathways Chart
  • LipidMetabolomics
  • Cofactor
  • Cofactors
  • Enzymes, Inhibitors, and Substrates
  • Metabolic Libraries
  • Metabolites and Cofactors on the Metabolic Pathways Chart
  • Pantothenate
  • Pharmaceutical