Nocloprost

Product Name: Nocloprost
CAS No.: 79360-43-3
Chemical Name: Nocloprost
Synonyms: SH-475;Nocloprost;(5Z,13E,15R)-9β-Chloro-11α,15-dihydroxy-16,16-dimethylprosta-5,13-dien-1-oic acid;Prosta-5,13-dien-1-oicacid, 9-chloro-11,15-dihydroxy-16,16-dimethyl-, (5Z,9b,11a,13E,15R)-;Prosta-5,13-dien-1-oic acid, 9-chloro-11,15-dihydroxy-16,16-dimethyl-, (5Z,9β,11α,13E,15R)-
CBNumber: CB91179344
Molecular Formula: C22H37ClO4
Formula Weight: 400.983
MOL File: 79360-43-3.mol

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Nocloprost Property

Boiling point:: 539.8±50.0 °C(Predicted)
Density: 1.10±0.1 g/cm3(Predicted)
solubility: DMF: 11 mg/ml; DMSO: 10 mg/ml; Ethanol: 16 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
pka: 4.76±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10988
Product name: Nocloprost
Purity: ≥98%
Packaging: 500μg
Price: $166
Updated: 2024/03/01

Cayman Chemical

Product number: 10988
Product name: Nocloprost
Purity: ≥98%
Packaging: 1mg
Price: $241
Updated: 2024/03/01

Cayman Chemical

Product number: 10988
Product name: Nocloprost
Purity: ≥98%
Packaging: 5mg
Price: $933
Updated: 2023/06/20

TRC

Product number: N634150
Product name: Nocloprost
Packaging: 10mg
Price: $1470
Updated: 2021/12/16

TRC

Product number: N634150
Product name: Nocloprost
Packaging: 5mg
Price: $775
Updated: 2021/12/16

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Nocloprost Chemical Properties,Usage,Production

Uses

Nocloprost is a synthetic prostaglandin E (P838610) analogue which can stimulate adenylate cyclase enzyme. Nocloprost was also studied as mucosal protective drug.

in vivo

Nocloprost (intragastrically; 0.01-10 μg/kg) 30 min before 100% ethanol, acidified Aspirin (HY-14654), acidified Taurocholate (HY-N0545), water immersion, or restraint stress dose dependently prevents the formation of gastric lesions in rats^[1].
Nocloprost (i.g.; 0.01-100 μg/kg) failes to affect gastric acid secretion or intestinal secretion (enteropooling) but preventes the increased gastroduodenal alkaline secretion^[1].
Nocloprost (s.c.) shows protective activity against ethanol damage but is ineffective when applied intraduodenally^[1].

Animal Model:	220-250 g rats^[1]
Dosage:	0.01-10 μg/kg
Administration:	Intragastrically; single dose
Result:	30 min before 100% ethanol, acidified Aspirin (ASA), acidified Taurocholate, water immersion, or restraint stress dose dependently prevented the formation of gastric lesions, the ID₅₀ values being 0.25, 0.58, 0.06 and 0.12 μg/kg in rats, respectively.

IC 50

EP1; EP3

Nocloprost Preparation Products And Raw materials

Raw materials

Preparation Products

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Nocloprost Suppliers

China 30 United States 4 Global 34

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24960
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11972
Advantage: 58

Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
Country: China
ProdList: 6838
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
Email: support@targetmol.com
Country: United States
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Advantage: 58

Aoki Biotechnology (Shenzhen) Co., Ltd.

Tel: 18566777408
Country: CHINA
ProdList: 6056
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79360-43-3, NocloprostRelated Search:

Nocloprost

(5Z,13E,15R)-9β-Chloro-11α,15-dihydroxy-16,16-dimethylprosta-5,13-dien-1-oic acid

SH-475

Prosta-5,13-dien-1-oic acid, 9-chloro-11,15-dihydroxy-16,16-dimethyl-, (5Z,9β,11α,13E,15R)-

Prosta-5,13-dien-1-oicacid, 9-chloro-11,15-dihydroxy-16,16-dimethyl-, (5Z,9b,11a,13E,15R)-

79360-43-3