Oxypendyl
- Product Name
- Oxypendyl
- CAS No.
- 5585-93-3
- Chemical Name
- Oxypendyl
- Synonyms
- Oxipendyl;Oxypendyl;2-[4-(3-pyrido[3,2-b][1,4]benzothiazin-10-ylpropyl)piperazin-1-yl]ethanol;4-[3-(10H-Pyrido[3,2-b][1,4]benzothiazin-10-yl)propyl]-1-piperazineethanol;1-Piperazineethanol, 4-[3-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)propyl]-
- CBNumber
- CB91179430
- Molecular Formula
- C20H26N4OS
- Formula Weight
- 370.51
- MOL File
- 5585-93-3.mol
Oxypendyl Property
- Boiling point:
- bp1 260-265°; bp6 280-300°
N-Bromosuccinimide Price
- Product number
- API0012169
- Product name
- OXYPENDYL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.39
- Updated
- 2021/12/16
Oxypendyl Chemical Properties,Usage,Production
Originator
Pervetral, Homburg , W. Germany ,1962
Definition
ChEBI: Oxypendyl is a tertiary amino compound and an aromatic amine.
Manufacturing Process
32 parts of 10-(γ-N-piperazinopropyl)-4-azaphenthiazine in 200 cc of butanol with 9 parts of ethylene chlorohydrin and 14 parts of finely powdered potash are heated for 4 hours under reflux while stirring vigorously. After cooling, extraction is carried out with dilute hydrochloric acid, the substance is finally washed with water and the combined hydrochloric acid aqueous phase is washed twice with ether. The base is then liberated with concentrated sodium hydroxide solution and taken up in chloroform. The chloroform solution is dried with potash and concentrated by evaporation. 26.4 parts of (10-γ-N-Bhydroxyethylpiperazino-N1-propyl)-4-azaphenthiazine are distilled over at 280°C to 300°C/6 mm. The dihydrochloride is obtained in isopropanol with isopropanolic hydrochloric acid. The product melts at 218°C to 220°C.
Therapeutic Function
Antiemetic