Vatanidipine
- Product Name
- Vatanidipine
- CAS No.
- 116308-55-5
- Chemical Name
- Vatanidipine
- Synonyms
- AE0047;WATA-012;Vatanidipine;Watanidipine;Vatanidipine, 10 mM in DMSO;2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[4-(4-benzhydryl-1-piperazinyl)phenethyl]5-methyl ester;2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-methyl 5-[2-[4-[(4-benzhydrylpiperazin)-1-yl]phenyl]ethyl] ester;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[4-[4-(diphenylmethyl)-1-piperazinyl]phenyl]ethyl] 5-methyl ester
- CBNumber
- CB91180041
- Molecular Formula
- C41H42N4O6
- Formula Weight
- 686.805
- MOL File
- 116308-55-5.mol
Vatanidipine Property
- Boiling point:
- 799.4±60.0 °C(Predicted)
- Density
- 1.237±0.06 g/cm3(Predicted)
- pka
- 7.11±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- API0004577
- Product name
- VATANIDIPINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.63
- Updated
- 2021/12/16
Vatanidipine Chemical Properties,Usage,Production
Uses
Vatanidipine (Watanidipine) is an orally active dihydropyridine (DHP)-type calcium channel blocker and a useful antihypertensive agent. Vatanidipine shows vasodilatory effects and also suppresses noradrenaline release from sympathetic nerve endings[1][2].
in vivo
Vatanidipine (1-10 mg/kg, p.o.) suppresses the systolic blood pressure of spontaneously hypertensive rats[1].
References
[1] Matsumura Y, et al. Vatanidipine hydrochloride: a new long-lasting antihypertensive agent. Expert Opin Investig Drugs. 2001 Jan;10(1):139-55. DOI:10.1517/13543784.10.1.139
[2] H Shinyama, et al. Effects of the calcium antagonist AE0047 on the development of neurological deficit and infarction after middle cerebral artery occlusion in stroke-prone spontaneously hypertensive rats. J Pharm Pharmacol. 1997 Sep;49(9):919-24. DOI:10.1111/j.2042-7158.1997.tb06136.x
Vatanidipine Preparation Products And Raw materials
Raw materials
Preparation Products
Vatanidipine Suppliers
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View Lastest Price from Vatanidipine manufacturers
- Product
- Vatanidipine 116308-55-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97%-99.9%
- Supply Ability
- 100kg
- Release date
- 2019-12-26