6-bromo-8-nitroquinoline
- Product Name
- 6-bromo-8-nitroquinoline
- CAS No.
- 68527-67-3
- Chemical Name
- 6-bromo-8-nitroquinoline
- Synonyms
- 6-bromo-8-nitroquinoline;Quinoline, 6-bromo-8-nitro-
- CBNumber
- CB91180450
- Molecular Formula
- C9H5BrN2O2
- Formula Weight
- 253.05
- MOL File
- 68527-67-3.mol
6-bromo-8-nitroquinoline Property
- Melting point:
- 170-177 °C
- Boiling point:
- 365.8±27.0 °C(Predicted)
- Density
- 1.747±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 0.41±0.20(Predicted)
- Appearance
- Yellow to brown Solid
- EPA Substance Registry System
- 6-Bromo-8-nitroquinoline (68527-67-3)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- CS-0041422
- Product name
- 6-Bromo-8-nitroquinoline
- Purity
- ≥97.0%
- Packaging
- 100mg
- Price
- $82
- Updated
- 2021/12/16
- Product number
- CS-0041422
- Product name
- 6-Bromo-8-nitroquinoline
- Purity
- ≥97.0%
- Packaging
- 1g
- Price
- $130
- Updated
- 2021/12/16
- Product number
- CS-0041422
- Product name
- 6-Bromo-8-nitroquinoline
- Purity
- ≥97.0%
- Packaging
- 250mg
- Price
- $168
- Updated
- 2021/12/16
- Product number
- HCH0359740
- Product name
- 6-BROMO-8-NITROQUINOLINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.13
- Updated
- 2021/12/16
- Product number
- CS-0041422
- Product name
- 6-Bromo-8-nitroquinoline
- Purity
- ≥97.0%
- Packaging
- 5g
- Price
- $518
- Updated
- 2021/12/16
6-bromo-8-nitroquinoline Chemical Properties,Usage,Production
Chemical Properties
yellow powder
Synthesis
875-51-4
107-21-1
68527-67-3
1. Add H2O (20 mL) to a 250 mL flask and place in an ice bath to cool. H2SO4 (50 mL) was added slowly to prepare a sulfuric acid solution. 2. To the above sulfuric acid solution, glycerol (12 mL, 16.5 mmol), m-nitrobenzenesulfonic acid sodium salt (11.4 g, 5.06 mmol), and 4-bromo-2-nitroaniline (10 g, 4.6 mmol) were added sequentially. 3. The reaction mixture was heated to 135 °C with continuous stirring for 3 hours. 4. Upon completion of the reaction, the warmed reaction mixture was slowly poured into ice H2O (200 mL). 5. The reaction mixture was extracted with 50% MeOH/EtOAc solvent mixture (2 x 200 mL). 6. The organic phases were combined and dried with Na2SO4, followed by concentration of the organic phase. 7. The resulting brown solid was ground with EtOH and filtered to give the pink solid product 6-bromo-8-nitroquinoline (3.8 g, 33% yield) with a melting point of 172-174 °C.
References
[1] Patent: EP1147083, 2004, B1. Location in patent: Page 45-46
6-bromo-8-nitroquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
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