ChemicalBook > CAS DataBase List > Ethyl 4-acetylbutyrate

Ethyl 4-acetylbutyrate

Product Name
Ethyl 4-acetylbutyrate
CAS No.
13984-57-1
Chemical Name
Ethyl 4-acetylbutyrate
Synonyms
Ethyl 5-oxohexanoate;Hexanoic acid, 5-oxo-, ethyl ester;ETHYL 4-ACETYLBUTYRATE;Ethyl 4-acetylbutanoate;Ethyl 4-acetylbutyrate 98%;Ethyl 4-Acetylbutyrate,>96%;5-oxo-hexanoicaciethylester;Ethyl 4-Acetylbutyrate,>98%;4-Acetylbutyricacidethylester;Ethyl-4-acetylbutyrate, GC 98%
CBNumber
CB9119477
Molecular Formula
C8H14O3
Formula Weight
158.2
MOL File
13984-57-1.mol
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Ethyl 4-acetylbutyrate Property

Boiling point:
221-222 °C(lit.)
Density 
0.989 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.427(lit.)
Flash point:
157 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Sparingly), Methanol (Slightly)
form 
Oil
color 
Colourless
BRN 
1762625
InChI
InChI=1S/C8H14O3/c1-3-11-8(10)6-4-5-7(2)9/h3-6H2,1-2H3
InChIKey
MGPSIDGTLFKDEY-UHFFFAOYSA-N
SMILES
C(OCC)(=O)CCCC(=O)C
EPA Substance Registry System
Ethyl 5-oxohexanoate (13984-57-1)
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Safety

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
2918300090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

Precautionary statements

P403+P235Store in a well-ventilated place. Keep cool.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
192090
Product name
Ethyl 4-acetylbutyrate
Purity
98%
Packaging
25g
Price
$105.6
Updated
2024/03/01
Alfa Aesar
Product number
L17848
Product name
Ethyl 4-acetylbutyrate, 97%
Packaging
5g
Price
$36.65
Updated
2024/03/01
Alfa Aesar
Product number
L17848
Product name
Ethyl 4-acetylbutyrate, 97%
Packaging
25g
Price
$116.65
Updated
2024/03/01
Alfa Aesar
Product number
L17848
Product name
Ethyl 4-acetylbutyrate, 97%
Packaging
100g
Price
$292.65
Updated
2024/03/01
TRC
Product number
O856865
Product name
5-OxohexanoicAcidEthylEster
Packaging
25g
Price
$220
Updated
2021/12/16
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Ethyl 4-acetylbutyrate Chemical Properties,Usage,Production

Uses

Ethyl 4-acetylbutyrate is used to prepare tyrosine-derived RGD peptidomimetics containing oligoethylene glycol (OEG) spacers. It is also used to synthesize constrained glycyl amides derived from RGD tripeptide as nonpeptide αvβ3 antagonists.

Synthesis

30ml of acetone and 11.5mmol of tetrahydropyrrole were added to a dry three-necked flask equipped with a thermometer and reflux condenser, and then slowly add 50mmol of ethyl acrylate dropwise at 60°C for 10h. After the reaction, the reaction solution is at 60°C Distill the remaining unreacted acetone and acidify with dilute hydrochloric acid to adjust the pH to 4. Add ethyl acetate for extraction, collect the organic layer, and perform preliminary vacuum distillation at 0.1MPa vacuum and 45°C to distill off the low-boiling solvent, followed by 3- Collect 70-80°C fractions under a vacuum of 7mmHg to prepare Ethyl 4-acetylbutyrate.

Ethyl 4-acetylbutyrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 4-acetylbutyrate Suppliers

China 90 Germany 2 India 4 Switzerland 2 United Kingdom 3 United States 10 Global 111
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View Lastest Price from Ethyl 4-acetylbutyrate manufacturers

Huida Pharmaceutical Technology (Shanghai) Co., Ltd.
Product
ETHYL 4-ACETYLBUTYRATE 13984-57-1
Price
US $0.00-0.00/kg
Min. Order
0.1kg
Purity
98%
Supply Ability
100kg
Release date
2023-03-07
Honest Joy Holdings Limited
Product
ETHYL 4-ACETYLBUTYRATE 13984-57-1
Price
US $60.00/KG
Min. Order
1000KG
Purity
99%
Supply Ability
20 tons
Release date
2022-01-05
Career Henan Chemical Co
Product
Ethyl 5-oxohexanoate 13984-57-1
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
as request
Release date
2018-12-25

13984-57-1, Ethyl 4-acetylbutyrateRelated Search:

DIETHYL 2-ACETYLGLUTARATE Ethyl 4-acetylbutyrate Limonin Acetonylsuccinic acid diethyl ester OBACUNON Ethyl 4-oxocyclohexanecarboxylate MEPARTRICIN Nomilin DIETHYL 3-OXOPIMELATE ETHYL 4-ACETYL-5-OXOHEXANOATE ETHYL 2-ACETYLBUTYRATE,Ethyl alpha-acetylbutyrate,Ethyl a-acetylbutyrate Ethyl butyrate 4-CARBETHOXY-3-METHYL-2-CYCLOHEXEN-1-ONE 4-CARBETHOXY-2-ETHYL-3-METHYL-2-CYCLOHEXEN-1-ONE ETHYL 5-OXO-5-PHENYLVALERATE 4,7-BIS(4-CHLOROPHENYL)-4,6,7,8-TETRAHYDRO-2H-CHROMENE-2,5(3H)-DIONE 4-(4-METHOXYPHENYL)-7,7-DIMETHYL-4,6,7,8-TETRAHYDRO-2H-CHROMENE-2,5(3H)-DIONE 4-(4-CHLOROPHENYL)-7,7-DIMETHYL-4,6,7,8-TETRAHYDRO-2H-CHROMENE-2,5(3H)-DIONE

  • 5-Oxohexanoic acid ethyl ester
  • 5-oxo-hexanoicaciethylester
  • Ethyl 5-oxohexanoate
  • ETHYL 4-ACETYLBUTYRATE
  • 4-Acetylbutyricacidethylester
  • Hexanoic acid, 5-oxo-, ethyl ester
  • Ethyl 4-acetylbutanoate
  • 5-Ketocaproic acid ethyl ester
  • Ethyl-4-acetylbutyrate, GC 98%
  • Ethyl 4-acetylbutyrate 98%
  • Ethyl 4-Acetylbutyrate,>96%
  • Ethyl 4-Acetylbutyrate,>98%
  • Hexanoic acid, 5-oxo-, ethyl ester (6CI, 8CI, 9CI, ACI)
  • 5-oxo-Hexanoic acid ethyl ester (6CI 8CI 9CI ACI)
  • 13984-57-1
  • CH3COCH23CO2C2H5
  • ESTER
  • Plasticizers
  • Polymer Additives
  • Polymer Science