ChemicalBook > CAS DataBase List > 1-NAPHTHOL-3,6,8-TRISULFONIC ACID TRISODIUM SALT
1-NAPHTHOL-3,6,8-TRISULFONIC ACID TRISODIUM SALT
- Product Name
- 1-NAPHTHOL-3,6,8-TRISULFONIC ACID TRISODIUM SALT
- CAS No.
- 31894-34-5
- Chemical Name
- 1-NAPHTHOL-3,6,8-TRISULFONIC ACID TRISODIUM SALT
- Synonyms
- ζ-Stat trisodium;I-Stat (trisodium);NSC37044 trisodium;Zeta-Stat trisodium;1-NAPHTHOL-3,6,8-TRISULFONIC ACID TRISODIUM SALT;1,3,6-Naphthalenetrisulfonic acid, 8-hydroxy-, trisodium salt
- CBNumber
- CB9120578
- Molecular Formula
- C10H5Na3O10S3
- Formula Weight
- 450.31
- MOL File
- 31894-34-5.mol
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1-NAPHTHOL-3,6,8-TRISULFONIC ACID TRISODIUM SALT Property
- form
- Solid
- color
- Light yellow to light brown
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0134051
- Product name
- ζ-Stattrisodium
- Packaging
- 5mg
- Price
- $400
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0297563
- Product name
- 1-NAPHTHOL-3,6,8-TRISULFONIC ACID TRISODIUM SALT
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.2
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0134051
- Product name
- ζ-Stattrisodium
- Packaging
- 10mg
- Price
- $680
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0134051
- Product name
- ζ-Stattrisodium
- Packaging
- 50mg
- Price
- $1900
- Updated
- 2021/12/16
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1-NAPHTHOL-3,6,8-TRISULFONIC ACID TRISODIUM SALT Chemical Properties,Usage,Production
Uses
ζ-Stat trisodium (NSC37044 trisodium) is a specific and atypical PKC-ζ inhibitor, with an IC50 of 5 μM. ζ-Stat trisodium can reduce melanoma cell lines proliferation and induce apoptosis, and has antitumor activity in vitro[1][2].
IC 50
aPKC-ζ: 5 μM (IC50)
References
[1] Ratnayake WS, et, al. Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors. Cell Adh Migr. 2018; 12(5):447-463. DOI:10.1080/19336918.2018.1471323
[2] Islam SMA, et, al. Atypical Protein Kinase-C inhibitors exhibit a synergistic effect in facilitating DNA damaging effect of 5-fluorouracil in colorectal cancer cells. Biomed Pharmacother. 2020 Jan; 121:109665. DOI:10.1016/j.biopha.2019.109665
1-NAPHTHOL-3,6,8-TRISULFONIC ACID TRISODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
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1-NAPHTHOL-3,6,8-TRISULFONIC ACID TRISODIUM SALT Suppliers
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31894-34-5, 1-NAPHTHOL-3,6,8-TRISULFONIC ACID TRISODIUM SALTRelated Search:
1,6-Naphthalenedisulfonic acid disodium salt
tetrasodium [8-hydroxy-7-[[2-hydroxy-5-methyl-4-[[3-[[2-(sulphooxy)ethyl]sulphonyl]phenyl]azo]phenyl]azo]naphthalene-1,3,6-trisulphonato(6-)]cuprate(4-)
1,3,6-NAPHTHALENETRISULFONIC ACID, SODIUM SALT, HYDRATE, MIXTURE OF ISOMERS
1-NAPHTHOL-3,8-DISULFONIC ACID
1-NAPHTHOL-8-SULFONIC ACID SODIUM SALT
DIRECT VIOLET 22
1-Hydroxynaphthalene-8-sulfonic acid
1,3,(6,7)-Naphthalenetrisulfonic acid trisodium salt hydrate
1-NAPHTHOL-3,8-DISULFONIC ACID DISODIUM SALT
1-NAPHTHOL-3,6,8-TRISULFONIC ACID TRISODIUM SALT