2-Pyridinecarboxylic acid, 5,6-dichloro-
- Product Name
- 2-Pyridinecarboxylic acid, 5,6-dichloro-
- CAS No.
- 88912-24-7
- Chemical Name
- 2-Pyridinecarboxylic acid, 5,6-dichloro-
- Synonyms
- Laftidine-B;5,6-dichloropicolinic acid;2,3Dichloro6carboxypyridine;5,6-Dichloropicolinic acid 98%;5,6-Dichloro-2-pyridinecarboxylicacid;5,6-Dichloropyridine-2-carboxylic acid;2-Pyridinecarboxylic acid, 5,6-dichloro-;5,6-Dichloropyridine-2-carboxylicacid,98%;5,6-Dichloro-2-pyridinecarboxylic acid 5,6dichloropicolinic acid
- CBNumber
- CB91211273
- Molecular Formula
- C6H3Cl2NO2
- Formula Weight
- 192
- MOL File
- 88912-24-7.mol
2-Pyridinecarboxylic acid, 5,6-dichloro- Property
- Boiling point:
- 342.1±37.0 °C(Predicted)
- Density
- 1.612±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 3.04±0.10(Predicted)
- form
- Solid
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(6(10)11)9-5(3)8/h1-2H,(H,10,11)
- InChIKey
- QOJNAEPFSUYAFL-UHFFFAOYSA-N
- SMILES
- C1(C(O)=O)=NC(Cl)=C(Cl)C=C1
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- D473975
- Product name
- 5,6-Dichloropicolinicacid
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FD140178
- Product name
- 5,6-Dichloropicolinic acid
- Packaging
- 1g
- Price
- $83
- Updated
- 2021/12/16
- Product number
- 077056
- Product name
- 5,6-Dichloropicolinic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $89
- Updated
- 2021/12/16
- Product number
- 4H58-5-AN
- Product name
- 5,6-Dichloropicolinic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 4H58-5-AN
- Product name
- 5,6-Dichloropicolinic acid
- Purity
- 98%
- Packaging
- 5G
- Price
- $269
- Updated
- 2021/12/16
2-Pyridinecarboxylic acid, 5,6-dichloro- Chemical Properties,Usage,Production
Uses
2-Pyridinecarboxylic acid, 5,6-dichlorois known for its role in the synthesis of pharmaceuticals and agrochemicals, as well as its utility as a building block in organic synthesis and a reagent in various chemical reactions.
Synthesis
1415898-80-4
88912-24-7
5-Chloro-1-yloxy-pyridine-2-carboxylic acid (CAS: 1415898-80-4, 1.2 g, 7 mmol) was used as a raw material and was slowly added to phosphorus trichloride (POCl3, 10 g) at 0 °C. The reaction mixture was warmed up to 95 °C and maintained at this temperature for 1 hour. After completion of the reaction, the mixture was concentrated to dryness under reduced pressure. The residue was dissolved in water (15 mL) and extracted with ethyl acetate (2 × 15 mL). The organic phases were combined and washed sequentially with water (2 × 30 mL) and saturated saline (30 mL). The organic phase was dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford 5,6-dichloro-2-pyridinecarboxylic acid (1 g, 75% yield) as a yellow solid. The product was confirmed by mass spectrometry (EI), m/e = 191.9 [M + H]+.
References
[1] Patent: US2012/316147, 2012, A1. Location in patent: Page/Page column 66
[2] Patent: WO2012/168350, 2012, A1. Location in patent: Page/Page column 140
2-Pyridinecarboxylic acid, 5,6-dichloro- Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Pyridinecarboxylic acid, 5,6-dichloro- manufacturers
- Product
- 2-Pyridinecarboxylic acid, 5,6-dichloro- 88912-24-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-08