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Teicoplanin A2-5

Product Name
Teicoplanin A2-5
CAS No.
91032-38-1
Chemical Name
Teicoplanin A2-5
Synonyms
teicoplanin A2-5;Teichomycin A2-5;Teicoplanin A2-5 DISCONTINUED. Please see T015500;34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(9-methyl-1-oxodecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-ristomycinAaglycone;Ristomycin A aglycone, 34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(9-methyl-1-oxodecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-;Ristomycin A aglycone, 34-O-2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-2-deoxy-2-(9-methyl-1-oxodecyl)amino-.beta.-D-glucopyranosyl-42-O-.alpha.-D-mannopyranosyl-
CBNumber
CB91215185
Molecular Formula
C89H99Cl2N9O33
Formula Weight
1893.68
MOL File
91032-38-1.mol
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Teicoplanin A2-5 Property

Density 
1.67±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in ethanol;Soluble in methanol;Soluble in DMSO;Soluble in dimethyl formamide
form 
lyophilisate
pka
2.88±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20192
Product name
Teicoplanin A2-5
Purity
≥98%
Packaging
1mg
Price
$242
Updated
2024/03/01
Cayman Chemical
Product number
20192
Product name
Teicoplanin A2-5
Purity
≥98%
Packaging
5mg
Price
$965
Updated
2024/03/01
ApexBio Technology
Product number
C4938
Product name
TeicoplaninA2-5
Packaging
5mg
Price
$1104
Updated
2021/12/16
AK Scientific
Product number
6172CX
Product name
TeicoplaninA2-5
Packaging
5mg
Price
$1174
Updated
2021/12/16
ApexBio Technology
Product number
C4938
Product name
TeicoplaninA2-5
Packaging
1mg
Price
$276
Updated
2021/12/16
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Teicoplanin A2-5 Chemical Properties,Usage,Production

Uses

Teicoplanin A2-5 is an antibiotic against Gram positive bacteria.

Uses

Teicoplanin A2-5 is the most non-polar analogue of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. Teicoplanins possess potent broad spectrum antibiotic activity against Gram positive bacteria, including MRSA and E. faecalis.

Definition

ChEBI: A teicoplanin A2 that has 9-methyldecanoyl as the variable N-acyl group.

Biological Activity

teicoplanin a2-5, derived from actinoplanes teichomyceticus, is a glycopeptide antibiotic which produces a broad spectrum of antibiotic activity against gram-positive bacteria.teicoplanin a2-5 is the most non-polar metabolite in the family of teicoplanins. teicoplanin, previously referred to in the literature as teichomycin, is a mixture of five closely related components of similar polarity, designated t-a2-1, 2, 3, 4 and 5 and of one more polar component, designated t-a3. additionally, as a glycopeptide antibiotic belonging to the same family as vancomycin, teicoplanin blocks cell wall synthesis in bacillus subtilis, which is accompanied by an intracellular accumulation of udp-n-acetylmuramyl-pentapetide [1]. due to the greater antibacterial activity of teicoplanin than other agents, it has been thoroughly studied as a β-1actamase-resistant agent for the treatment of human infections caused by streptococci and staphylococci, including enterococci [2].

References

[1]. somma, s., gastaldo, l., & corti, a. teicoplanin, a new antibiotic from actinoplanes teichomyceticus nov. sp. antimicrobial agents and chemotherapy. 1984; 26(6): 917-923.
[2]. traina, g., & bonati, m. pharmacokinetics of teicoplanin in man after intravenous administration. journal of pharmacokinetics and biopharmaceutics. 1984;12(2): 119-128.

Teicoplanin A2-5 Preparation Products And Raw materials

Raw materials

Preparation Products

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Teicoplanin A2-5 Suppliers

ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
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BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
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Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Country
China
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Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
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United Kingdom
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
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57412
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BOC Sciences
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+1-631-485-4226
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1-631-614-7828
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inquiry@bocsci.com
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United States
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
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sales@chemegen.com
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China
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Meng Cheng Technology (Shanghai) Co., LTD
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400-820-6829
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sales@mitachieve.com
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China
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8860
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MedBioPharmaceutical Technology Inc
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021-69568360 18916172912
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order@med-bio.cn
Country
China
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8140
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58
Shanghai Saikerui Biotechnology Co. , Ltd.
Tel
021-58000709 15900491054
Email
info@scrbio.com
Country
China
ProdList
10329
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58

91032-38-1, Teicoplanin A2-5Related Search:


  • Ristomycin A aglycone, 34-O-2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-2-deoxy-2-(9-methyl-1-oxodecyl)amino-.beta.-D-glucopyranosyl-42-O-.alpha.-D-mannopyranosyl-
  • teicoplanin A2-5
  • Ristomycin A aglycone, 34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(9-methyl-1-oxodecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-
  • Teichomycin A2-5
  • Teicoplanin A2-5 DISCONTINUED. Please see T015500
  • 34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(9-methyl-1-oxodecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-ristomycinAaglycone
  • 91032-38-1