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2-FLUOROPHENYL CYCLOPENTYL KETONE

Product Name
2-FLUOROPHENYL CYCLOPENTYL KETONE
CAS No.
111982-45-7
Chemical Name
2-FLUOROPHENYL CYCLOPENTYL KETONE
Synonyms
2-FLUOROPHENYL CYCLOPENTYL KETONE;Cyclopentyl-(2-Fluorophenyl)methanone;Methanone, cyclopentyl(2-fluorophenyl)-
CBNumber
CB9121742
Molecular Formula
C12H13FO
Formula Weight
192.23
MOL File
111982-45-7.mol
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2-FLUOROPHENYL CYCLOPENTYL KETONE Property

Boiling point:
275.8±13.0 °C(Predicted)
Density 
1.131±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Oil
color 
Colourless
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
31035
Product name
2-Fluorophenyl Cyclopentyl Ketone
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
31035
Product name
2-Fluorophenyl Cyclopentyl Ketone
Packaging
5mg
Price
$109
Updated
2024/03/01
TRC
Product number
F632460
Product name
2-FluorophenylCyclopentylKetone
Packaging
100mg
Price
$180
Updated
2021/12/16
TRC
Product number
F632460
Product name
2-FluorophenylCyclopentylKetone
Packaging
1g
Price
$1340
Updated
2021/12/16
Rieke Metals
Product number
6123-03-37
Product name
2-Fluorophenylcyclopentylketone
Purity
97%
Packaging
1g
Price
$417
Updated
2021/12/16
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2-FLUOROPHENYL CYCLOPENTYL KETONE Chemical Properties,Usage,Production

Uses

2-Fluorophenyl cyclopentyl ketone is a precursor in the synthesis of fluoroketamine.

Synthesis

394-47-8

33240-34-5

111982-45-7

General procedure for the synthesis of 2-fluorophenylcyclopentanone from 2-fluorobenzonitrile and cyclopentylmagnesium bromide: 2-fluorobenzonitrile (5.0 g, 41.01 mmol) was added to 80 mL of THF containing 2 moles of cyclopentylmagnesium bromide in THF solution (20.51 mL, 41.01 mmol) and CuBr (0.100 g) under argon protection at 60 °C and the reaction was The reaction was stirred for 15 hours. After completion of the reaction, the reaction mixture was cooled to 0 °C, 5% sulfuric acid solution was added, and stirring was continued for 15 hours. Subsequently, the reaction mixture was extracted with ether three times. The organic layers were combined, dried with anhydrous MgSO4, concentrated and the residue was purified by column chromatography (eluent: a mixture of ethyl acetate and hexane) to afford the target product 2-fluorophenyl cyclopentanone (3.085 g, 40% yield). The mass spectrum (ES) showed m/z=192.15 (M+1)+.

References

[1] Patent: WO2005/66126, 2005, A1. Location in patent: Page/Page column 83

2-FLUOROPHENYL CYCLOPENTYL KETONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-FLUOROPHENYL CYCLOPENTYL KETONE Suppliers

Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Rieke Metals, Inc.
Tel
--
Fax
--
Email
sales@riekemetals.com
Country
United States
ProdList
6509
Advantage
69
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View Lastest Price from 2-FLUOROPHENYL CYCLOPENTYL KETONE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-FLUOROPHENYL CYCLOPENTYL KETONE 111982-45-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-02-22
Shaanxi Dideu Medichem Co. Ltd
Product
2-Fluorophenyl cyclopentyl ketone 111982-45-7
Price
US $0.01-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2020-04-22