ChemicalBook > CAS DataBase List > N,N'-Dimethylarginine

N,N'-Dimethylarginine

Product Name
N,N'-Dimethylarginine
CAS No.
30344-00-4
Chemical Name
N,N'-Dimethylarginine
Synonyms
SDMA-d6;Dimethylarginine;SDMA, 10 mM in DMSO;Arginine Impurity 13;N,N'-Dimethylarginine;NG'-Dimethyl-L-arginine;Symmetric dimethylarginine;Nω,N'ω-dimethyl-L-arginine;NG,NG’-Dimethy-L-arginine-d6;L-Arg(Me, Me)-OH (syMMetrical)
CBNumber
CB91236269
Molecular Formula
C8H18N4O2
Formula Weight
202.25
MOL File
30344-00-4.mol
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N,N'-Dimethylarginine Property

Boiling point:
353.5±52.0 °C(Predicted)
Density 
1.22±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO : 50 mg/mL (247.22 mM; ultrasonic and adjust pH to 3 with 1M HCl)
form 
Orange powder.
pka
2.48±0.24(Predicted)
color 
White to off-white
Stability:
Very Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-6304
Product name
SDMA
Purity
>98.0%
Packaging
100mg
Price
$103
Updated
2021/12/16
ChemScene
Product number
CS-6304
Product name
SDMA
Purity
>98.0%
Packaging
250mg
Price
$238
Updated
2021/12/16
ChemScene
Product number
CS-6304
Product name
SDMA
Purity
>98.0%
Packaging
1g
Price
$569
Updated
2021/12/16
CSNpharm
Product number
CSN25207
Product name
SDMA
Packaging
25mg
Price
$110
Updated
2021/12/16
Ambeed
Product number
A507261
Product name
(S)-2-Amino-5-((bis(methylamino)methylene)amino)pentanoicacid
Purity
98%
Packaging
100mg
Price
$115
Updated
2021/12/16
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N,N'-Dimethylarginine Chemical Properties,Usage,Production

Chemical Properties

Beige to Pale Yellow Solid

Uses

N,N'-Dimethylarginine is an arginine derivative; used in chronic kidney diseases. A potential endogenous nitric oxide inhibitor in dialysis.

Definition

ChEBI: A L-arginine derivative having two methyl groups at the Nomega- and N'omega-positions

in vivo

SDMA is highly stable in serum and plasma, and the assay demonstrates excellent analytical performance. In unaffected dogs, SDMA remains unchanged whereas in affected dogs, SDMA increases during disease progression, correlating strongly with an increase in sCr and decrease in GFR[3].
Chronic SDMA infusion leads to a significant increase of SDMA levels in mice, but the GFR did not change at 4 weeks. No histological changes are observed, particularly no effect on fibrosis or endothelias nitric oxide synthase expression. There is neither an effect of SDMA on systolic blood pressure nor on ejection fraction[4].

IC 50

Human Endogenous Metabolite

N,N'-Dimethylarginine Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N'-Dimethylarginine Suppliers

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View Lastest Price from N,N'-Dimethylarginine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
N,N'-Dimethylarginine 30344-00-4
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-11-24
Career Henan Chemical Co
Product
N,N'-Dimethylarginine 30344-00-4
Price
US $2.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
ask
Release date
2020-01-08

30344-00-4, N,N'-DimethylarginineRelated Search:

N,N'-Dimethyl-1,3-propanediamine N,N-Dimethylbenzylamine N,N-Dimethylbenzamide N,N-Dimethylpropionamide Asymmetric dimethylarginine

  • (2S)-2-amino-5-[(N,N'-dimethylcarbamimidoyl)amino]pentanoic acid
  • L-Arg(Me, Me)-OH (syMMetrical)
  • L-Arg(Me, Me)-OH (asyMMetrical)
  • Symmetric dimethylarginine
  • N5-[(Dimethylamino)iminomethyl]-L-ornithine-d6
  • N5-[Bis(methylamino)methylene]-L-ornithine-d6
  • NG,NG’-Dimethy-L-arginine-d6
  • SDMA-d6
  • (S)-2-Amino-5-((bis(methylamino)methylene)amino)pentanoic acid
  • NG,NG'-Dimethy-L-arginine Solution, 100ppm
  • NG'-Dimethyl-L-arginine
  • Nω,N'ω-dimethyl-L-arginine
  • L-Arg(Me,Me)-OH(symmetrical), >97%
  • L-Ornithine,N5-[(methylamino)(methylimino)methyl]-
  • N,N'-Dimethylarginine USP/EP/BP
  • inhibit,Inhibitor,Endogenous Metabolite,SDMA
  • (2S)-2-amino-5-[(N,N-dimethylcarbamimidoyl)amino]pentanoic
  • Symmetric dimethylarginine（SDMA）
  • SDMA, 10 mM in DMSO
  • N,N'-Dimethylarginine
  • Arginine Impurity 13
  • Dimethylarginine
  • 30344-00-4
  • 30135-93-6
  • C8H12D6N4O2
  • Isotope Labelled Compounds
  • Amino Acids & Derivatives
  • Intermediates & Fine Chemicals
  • Isotope Labeled Compounds
  • Pharmaceuticals