AIDS124653
- Product Name
- AIDS124653
- CAS No.
- 26903-26-4
- Chemical Name
- AIDS124653
- Synonyms
- NSC43067;NSC 43067;AIDS124653;NSC43067 >=98% (HPLC);1-(5-Methyl-thiophen-2-yl)-3-phenyl-propenone;1-(5-Methyl-2-thienyl)-3-phenyl-2-Propen-1-one;2-Propen-1-one, 1-(5-methyl-2-thienyl)-3-phenyl-
- CBNumber
- CB91244743
- Molecular Formula
- C14H12OS
- Formula Weight
- 228.31
- MOL File
- 26903-26-4.mol
AIDS124653 Property
- Boiling point:
- 379.8±42.0 °C(Predicted)
- Density
- 1.167±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: >20mg/mL
- form
- powder
- color
- light yellow to light tan
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H413May cause long lasting harmful effects to aquatic life
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- N0915
- Product name
- NSC43067
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $675
- Updated
- 2024/03/01
- Product number
- N0915
- Product name
- NSC43067
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $150
- Updated
- 2022/05/15
- Product number
- KIN0001259
- Product name
- NSC43067
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $754.95
- Updated
- 2021/12/16
AIDS124653 Chemical Properties,Usage,Production
Biochem/physiol Actions
NSC43067 is a Cyclin-dependent kinase (Cdk) inhibitor which binds to a novel conserved site on Cdk, presumably the p27 binding pocket. The binding apparently directly induces Cdk1, Cdk2, and Cdk4 protein aggregation. Cdks 1, 2, 4, and 6 are the key Cdks that regulate the cell cycle, and are a target for a cancer treatment. NSC43067 arrests the cell cycle at the G0/G1 phase at lower concentrations and at the G2/M cell cycle phase at higher concentrations. The action appears to be reversible.
AIDS124653 Preparation Products And Raw materials
Raw materials
Preparation Products
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