cis-4-Methylcyclohexylamine. Property

Melting point:

-8.5°C (estimate)

Boiling point:

154℃

Density 

0.844

refractive index 

1.4550 to 1.4590

Flash point:

27℃

solubility 

soluble in Chloroform, Dichloromethane, Ethyl Acetate

pka

10.58±0.70(Predicted)

form 

clear liquid

color 

Colorless to Light yellow

EPA Substance Registry System

cis-4-Methylcyclohexylamine (2523-56-0)

Safety

RIDADR 

UN 2734 8/3/PG II

HS Code 

2921.30.5000

HazardClass 

8/3

PackingGroup 

II

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

cis-4-Methylcyclohexylamine. Chemical Properties,Usage,Production

Chemical Properties

Red Oil

Uses

An reagent used in the synthesis of many biologically active compounds including kinase inhibitors, receptor agonists/antagonists and a variety of ligands.

Definition

ChEBI: 4-Methylcyclohexylamine is an amine.

General Description

A colorless viscous oily liquid with almost no odor. Contact with the skin, eyes and mucous membranes causes severe chemical burns. Toxic by skin absorption. Toxic ammonia and nitrogen oxides may be released upon exposure to fire.

Air & Water Reactions

Slowly decomposes in air to yield ammonia.

Reactivity Profile

cis-4-Methylcyclohexylamine. is incompatible with acids and oxidizing agents. Neutralizes acids exothermically to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Generates flammable gaseous hydrogen in combination with strong reducing agents, such as hydrides.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.