trifluoromethanesulfonanilide

Product Name: trifluoromethanesulfonanilide
CAS No.: 456-64-4
Chemical Name: trifluoromethanesulfonanilide
Synonyms: 1,1,1-trifluoro-N-phenylmethanesulfonamide;Phenyltriflamide;N-Phenyltriflamide;trifluoromethanesulfonanilide;Trifluoromethanesulfonaniline;N-Phenyltrifluoromethanesulfonamide;1,1,1-Trifluoromethanesulfonanilide;N-[(Trifluoromethyl)sulfonyl]aniline;N-Phenyl-1,1,1-trifluoromethanesulfonamide;1,1,1-Trifluoro-N-phenylmethanesulphonamide
CBNumber: CB91310457
Molecular Formula: C7H6F3NO2S
Formula Weight: 225.19
MOL File: 456-64-4.mol

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trifluoromethanesulfonanilide Property

Melting point:: 65-66℃
Boiling point:: 233.5±50.0 °C(Predicted)
Density: 1.539±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: powder to crystal
pka: 4.35±0.10(Predicted)
color: White to Almost white

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Safety

RIDADR: UN 2811 6.1/PG III
RTECS: PB0482000
HazardClass: 6.1
PackingGroup: III
HS Code: 2904100090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: T2985
Product name: Trifluoromethanesulfonanilide
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $116
Updated: 2025/07/31

TCI Chemical

Product number: T2985
Product name: Trifluoromethanesulfonanilide
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $389
Updated: 2025/07/31

TRC

Product number: T791095
Product name: 1,1,1-Trifluoro-N-phenylmethanesulfonamide
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Chem-Impex

Product number: 37185
Product name: Trifluoromethanesulfonanilide,98%(Assaybytitration,HPLC)
Purity: 98%(Assaybytitration,HPLC)
Packaging: 1G
Price: $11.2
Updated: 2021/12/16

Apolloscientific

Product number: PC448034
Product name: 1,1,1-Trifluoro-N-phenylmethanesulphonamide
Packaging: 1g
Price: $22
Updated: 2021/12/16

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trifluoromethanesulfonanilide Chemical Properties,Usage,Production

Synthesis Reference(s)

Tetrahedron Letters, 14, p. 3839, 1973 DOI: 10.1016/S0040-4039(01)87051-9

Synthesis

358-23-6

62-53-3

456-64-4

Under stirring conditions, 4 g (2.4 mL) of trifluoromethanesulfonic anhydride was slowly added dropwise to 15 mL of aniline. After the dropwise addition was completed, the reaction mixture was continued to be stirred for 30 minutes. Upon completion of the reaction, the reaction solution was acidified with 10% hydrochloric acid solution, followed by filtration to collect the precipitate precipitated. The precipitate was washed several times with water, dried and purified by sublimation. Finally 2.9 g (90% yield) of the target compound 1,1,1 -trifluoro-N-phenylmethanesulfonamide was obtained under vacuum as a white powder (19F NMR δF -75.30 ppm).

References

[1] Journal of the American Chemical Society, 2018, vol. 140, # 9, p. 3202 - 3205
[2] Russian Journal of Organic Chemistry, 2016, vol. 52, # 8, p. 1112 - 1117
[3] Zh. Org. Khim., 2016, vol. 52, # 8, p. 1122 - 1127,6
[4] Organic Letters, 2016, vol. 18, # 13, p. 3130 - 3133
[5] Tetrahedron, 1975, vol. 31, # 20, p. 2517 - 2521

trifluoromethanesulfonanilide Preparation Products And Raw materials

Raw materials

Preparation Products

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trifluoromethanesulfonanilide Suppliers

China 64 Europe 1 India 2 Japan 1 Switzerland 1 United Kingdom 1 United States 7 Global 77

Achemica

Tel: --
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Email: contact@achemica.com
Country: Switzerland
ProdList: 6155
Advantage: 50

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View Lastest Price from trifluoromethanesulfonanilide manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: trifluoromethanesulfonanilide 456-64-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-09

456-64-4, trifluoromethanesulfonanilideRelated Search:

Trifluoromethanesulfonyl bromide Trifluoromethyl trifluorovinyl ether Benzoic acid (trifluoromethanesulfonic acid)anhydride Saprisartan FLUORIDAMID trifluoromethanesulfonanilide MEFLUIDIDE N-Phenyl-bis(trifluoromethanesulfonimide) Nickel, bis[N-[1-ethyl-1,2,3,4-tetrahydro-6-[(1,3,4-thiadiazol-2-yl-kN3)azo-kN1]-7-quinolinyl]-1,1,1-trifluoromethanesulfonamidato-kN]- Nickel, bis[N-[6-[2-(4,5-dicyano-1-methyl-1H-imidazol-2-yl-kN3)diazenyl-kN1]-1,2,3,4-tetrahydro-1-methyl-7-quinolinyl]-1,1,1-trifluoromethanesulfonamidato-kN]- PERFLUIDONE Methanesulfonamide, 1,1,1-trifluoro-N-[1,2,3,4-tetrahydro-1-(2-methylpropyl)-7-quinolinyl]- Zinc,bis[1,1,1-trifluoro-N-[1,2,3,4-tetrahydro-1-(2-methylpropyl)-6-[(1,3,4-thiadiazol-2-yl-kN3)azo-kN1]-7-isoquinolinyl]methanesulfonamidato-kN]- Methanesulfonamide, N-(1-ethyl-1,2,3,4-tetrahydro-7-quinolinyl)-1,1,1-trifluoro- Triflumidate N-(2-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]SULFANYL)PHENYL)(TRIFLUORO)METHANESULFONAMIDE BIS(4-TRIFLUOROMETHYLSULFONAMIDOPHENYL)-1,4-DIISOPROPYLBENZENE C,C,C-TRIFLUORO-N,N-DIPHENYL-METHANESULFONAMIDE

trifluoromethanesulfonanilide

Methanesulfonamide, 1,1,1-trifluoro-N-phenyl-

1,1,1-trifluoro-N-phenylmethanesulfonamide

1,1,1-trifluoro-N-phenyl-methanesulfonamide

1,1,1-Trifluoromethanesulfonanilide

Methanesulfonanilide,1,1,1-trifluoro- (6CI,8CI)

1,1,1-Trifluoro-N-phenylmethanesulphonamide

N-Phenyl-1,1,1-trifluoromethanesulfonamide

N-Phenyltriflamide

N-Phenyltrifluoromethanesulfonamide

Phenyltriflamide

Trifluoromethanesulfonaniline

N-[(Trifluoromethyl)sulfonyl]aniline

1,1,1-Trifluoro-N-phenylmethanesulfonamide - [T93999]

456-64-4

456644