ChemicalBook > CAS DataBase List > atrasentan

atrasentan

Product Name
atrasentan
CAS No.
173937-91-2
Chemical Name
atrasentan
Synonyms
A-147627;atrasentan;(+)-A 127722;(+)-A 127722;Atrasentan (ABT-627);A127722, CID 5310990;(+)-A 127722; ABT-627; A 127722; ABT 627;Atrasentan,Endothelin Receptor,A 147627,ABT627,Inhibitor,inhibit,A147627,ABT 627;(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid;(2S,3S,4R)-4-(1,3-BENZODIOXOL-5-YL)-1-[2-(DIBUTYLAMINO)-2-OXOETHYL]-2-(4-METHOXYPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID
CBNumber
CB91320566
Molecular Formula
C29H38N2O6
Formula Weight
510.62
MOL File
173937-91-2.mol
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atrasentan Property

Melting point:
122-124°
Boiling point:
659.4±55.0 °C(Predicted)
Density 
1.188±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
3.49±0.60(Predicted)
color 
Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A793925
Product name
Atrasentan
Packaging
25mg
Price
$745
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0005136
Product name
ATRASENTAN
Purity
95.00%
Packaging
5MG
Price
$550
Updated
2021/12/16
CSNpharm
Product number
CSN18015
Product name
Atrasentan
Packaging
50mg
Price
$784
Updated
2021/12/16
CSNpharm
Product number
CSN18015
Product name
Atrasentan
Packaging
5mg
Price
$242
Updated
2021/12/16
Crysdot
Product number
CD31002983
Product name
Atrasentan
Purity
98+%
Packaging
5mg
Price
$250
Updated
2021/12/16
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atrasentan Chemical Properties,Usage,Production

Uses

Palliative treatment of bone pain due to metastatic prostate cancer and disease progression (endothelin (ETA) receptor antagonist).

Uses

Atrasentan is a selective antagonist of the endothelin-A (ETA) receptor and binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.

Definition

ChEBI: Atrasentan is a member of pyrrolidines.

atrasentan Preparation Products And Raw materials

Raw materials

Preparation Products

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atrasentan Suppliers

China 57 India 1 United Kingdom 1 United States 5 Global 64
Suzhou Haiben Pharmaceutical Co., Ltd
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View Lastest Price from atrasentan manufacturers

Career Henan Chemical Co
Product
atrasentan 173937-91-2
Price
US $0.01/KG
Min. Order
1KG
Purity
98%; 99%
Supply Ability
500g;1kg； 25kg
Release date
2020-01-09

173937-91-2, atrasentanRelated Search:

tert-Butyl ethyl ether Aspartame Benzo[a]pyrene Selenium dioxide DIOXOPROMETHAZINE HCL 1,4-Dioxane 2-(2-Aminoethylamino)ethanol atrasentan

  • atrasentan
  • (2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid
  • (+)-A 127722
  • A-147627
  • (2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid
  • (2S,3S,4R)-4-(1,3-BENZODIOXOL-5-YL)-1-[2-(DIBUTYLAMINO)-2-OXOETHYL]-2-(4-METHOXYPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID
  • A127722, CID 5310990
  • Atrasentan (ABT-627)
  • (+)-A 127722; ABT-627; A 127722; ABT 627
  • Atrasentan [2R,3R,4S]-2-(4-methoxyphenyl)-4-(1,3-benzodioxol-5-yl)-1-[[(N,N-dibutylamino)-carboxyl]methyl]pyrrolidine-3-carboxylic acid
  • 3-Pyrrolidinecarboxylic acid, 4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-, (2R,3R,4S)-
  • (2R,3R,4S)-4-(Benzod1,3dioxol-5-yl)-1-(2-(dibutylamino)-2-oxoethyl)-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid.HCl
  • (+)-A 127722
  • Atrasentan,Endothelin Receptor,A 147627,ABT627,Inhibitor,inhibit,A147627,ABT 627
  • 173937-91-2
  • API