ChemicalBook > CAS DataBase List > SIM 6080
SIM 6080
- Product Name
- SIM 6080
- CAS No.
- 118790-68-4
- Chemical Name
- SIM 6080
- Synonyms
- SIM 6080;SIM6080,SIM 6080;1,2-Ethanediamine, N1-[3,3-bis(4-fluorophenyl)propyl]-N1,N2-dimethyl-N2-[(3,4,5-trimethoxyphenyl)methyl]-
- CBNumber
- CB91322050
- Molecular Formula
- C29H36F2N2O3
- Formula Weight
- 498.6
- MOL File
- 118790-68-4.mol
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SIM 6080 Property
- Boiling point:
- 556.8±50.0 °C(Predicted)
- Density
- 1.131±0.06 g/cm3(Predicted)
- pka
- 8.18±0.50(Predicted)
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SIM 6080 Chemical Properties,Usage,Production
Description
SIM-6080 is a calcium channel antagonist for the treatment of hyperlipidemia and myocardia ischemia. _x000D_ SIM-6080 inhibited the proliferation of rat aortic myocytes.
Uses
SIM-6080 is a calcium antagonist and inhibits the proliferation of rat aortic myocytes and reduces aortic atherosclerosis in rabbits[1][2].
References
[1] Bernini F, et al. In vitro inhibition of arterial myocyte growth and stimulation of low density lipoprotein metabolism by SIM 6080, a new calcium antagonist. Pharmacol Res. 1990;22(1):27-35. DOI:10.1016/1043-6618(90)90740-5
[2] Maggi FM, et al. SIM 6080, a new calcium antagonist, reduces aortic atherosclerosis in cholesterol-fed rabbits. Pharmacol Res. 1993;28(3):219-227. DOI:10.1006/phrs.1993.1125
SIM 6080 Preparation Products And Raw materials
Raw materials
Preparation Products
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SIM 6080 Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
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- 15002134094
- marketing@targetmol.cn
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- China
- ProdList
- 29357
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- Tel
- +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
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- Advantage
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