L 652343
- Product Name
- L 652343
- CAS No.
- 102565-09-3
- Chemical Name
- L 652343
- Synonyms
- 343;L652;L-652;L 652;L 652343;Benzo[b]thiophene-2-carboxamide, 3-hydroxy-N-[2-phenyl-2-(2-thienyl)ethenyl]-5-(trifluoromethyl)-, (E)- (9CI)
- CBNumber
- CB91326407
- Molecular Formula
- C22H14F3NO2S2
- Formula Weight
- 445.48
- MOL File
- 102565-09-3.mol
L 652343 Property
- Boiling point:
- 634.2±55.0 °C(Predicted)
- Density
- 1.436±0.06 g/cm3(Predicted)
- pka
- 6?+-.0.50(Predicted)
L 652343 Chemical Properties,Usage,Production
Description
L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro and inhibits the synthesis of the products of both these pathways in whole cells.
Uses
(E)-L-652343 is a compound with potent cyclooxygenase and 5-lipoxygenase inhibitory activity. (E)-L-652343 can effectively inhibit the synthesis of products of these two pathways in vivo. (E)-L-652343 showed high sensitivity and specificity in the detection of geometric isomers in canine and human plasma. (E)-L-652343 showed selective metabolism in vivo, and the elimination rate of the E isomer was faster than that of the Z isomer[1].
References
[1] Stereoselective disposition of the geometric isomers of a novel lipoxygenase cyclo-oxygenase inhibitor in dog and photochemical interconversion of its isomers
L 652343 Preparation Products And Raw materials
Raw materials
Preparation Products
L 652343 Suppliers
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- +1-781-999-5354; +17819995354
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- United States
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- China
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- +17819995354
- marketing@targetmol.com
- Country
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