LY 245769

Product Name: LY 245769
CAS No.: 127345-02-2
Chemical Name: LY 245769
Synonyms: LY 245769;Benzenemethanol, 3-(1H-tetrazol-5-yl)-α-[(1R,2E,4Z)-14,14,14-trifluoro-1-[[2-(1H-tetrazol-5-yl)ethyl]thio]-2,4-tetradecadienyl]-, (αS)- (9CI)
CBNumber: CB91332765
Molecular Formula: C25H33F3N8OS
Formula Weight: 550.6427296
MOL File: 127345-02-2.mol

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LY 245769 Property

Boiling point:: 746.8±70.0 °C(Predicted)
Density: 1.286±0.06 g/cm3(Predicted)
pka: 4.23±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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LY 245769 Chemical Properties,Usage,Production

Description

LY 245769 is a leukotriene E4 (LTE4) inhibitor.

Uses

LY 245769, a omega-trifluoro analog, is a leukotriene E4 (LTE4) inhibitor. LY 245769 interfers the omega-oxidation of N-acetyl-LTE4 and leukotriene B4 (LTB4) with IC50s of 4 μM[1].

References

[1] G Jedlitschky, et al. Inhibition of leukotriene omega-oxidation by omega-trifluoro analogs of leukotrienes. Arch Biochem Biophys. 1990 Nov 1;282(2):333-9. DOI:10.1016/0003-9861(90)90125-i

LY 245769 Preparation Products And Raw materials

Raw materials

Preparation Products

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LY 245769 Suppliers

China 1 South Korea 1 United States 1 Global 3

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29257
Advantage: 58

127345-02-2, LY 245769Related Search:

LY 245769

Benzenemethanol, 3-(1H-tetrazol-5-yl)-α-[(1R,2E,4Z)-14,14,14-trifluoro-1-[[2-(1H-tetrazol-5-yl)ethyl]thio]-2,4-tetradecadienyl]-, (αS)- (9CI)

127345-02-2