epsilon-viniferin
- Product Name
- epsilon-viniferin
- CAS No.
- 62218-08-0
- Chemical Name
- epsilon-viniferin
- Synonyms
- e-viniferin;Ε-VINIFERIN;ε-Viniferin-RM;epsilon-viniferin;trans-ε-Viniferin;epsilion-Viniferin;ε-Viniferin Standard;(-)-trans-ε-viniferin;ε-Viniferin, 10 mM in DMSO;(-)-trans-epsilon-viniferin
- CBNumber
- CB91337184
- Molecular Formula
- C28H22O6
- Formula Weight
- 454.47
- MOL File
- 62218-08-0.mol
epsilon-viniferin Property
- Melting point:
- approximate 157℃ (dec.)
- storage temp.
- Store at -20°C
- solubility
- Soluble in methanol;
- form
- Powder
- color
- Off-white to gray
- Water Solubility
- sparingly soluble in water
- LogP
- 3.802 (est)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- PHL83550
- Product name
- ε-Viniferin
- Purity
- phyproof? Reference Substance
- Packaging
- 10MG
- Price
- $333
- Updated
- 2023/01/07
- Product number
- 25737
- Product name
- trans-ε-Viniferin
- Packaging
- 500μg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 25737
- Product name
- trans-ε-Viniferin
- Packaging
- 1mg
- Price
- $115
- Updated
- 2024/03/01
- Product number
- FV30429
- Product name
- epsilon-Viniferin
- Packaging
- 1mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- FV30429
- Product name
- epsilon-Viniferin
- Packaging
- 2mg
- Price
- $200
- Updated
- 2021/12/16
epsilon-viniferin Chemical Properties,Usage,Production
Description
trans-ε-Viniferin is a stilbene polyphenol and dimer of trans-resveratrol that has been found in various red wines and has diverse biological activities. It induces disaggregation of aggregated amyloid-β (1-42) (Aβ42; ) fibrils in a cell-free assay and decreases Aβ42- and IL-1β-induced release of TNF-α and IL-6 in primary mouse neuron and astrocyte cocultures. trans-ε-Viniferin reduces cytotoxicity induced by truncated huntingtin (Htt) in PC12 cells (EC50 = 30 nM). It also reduces production of reactive oxygen species (ROS), mitochondrial dysfunction, and PGC-1α depletion and increases protein levels and deacetylase activity of sirtuin 3 (SIRT3) in cells expressing mutant Htt. trans-ε-Viniferin inhibits calcium-activated chloride channel currents in HT-29 cells (IC50 = ~1 μM). In vivo, trans-ε-viniferin (2 μg per animal) reduces rotavirus-induced secretory diarrhea in mice without affecting the rotaviral infection. Dietary administration of trans-ε-viniferin reduces hepatic triglyceride accumulation and body weight increases in a mouse model of diet-induced obesity.
Uses
ε-Viniferin is a stilbene extract posessing cytotoxic effects and may contain anti-cancer properties.
Definition
ChEBI: (-)-trans-epsilon-viniferin is a stilbenoid that is the (-)-trans-stereoisomer of epsilon-viniferin, obtained by cyclodimerisation of trans-resveratrol. It has a role as a metabolite. It is a member of 1-benzofurans, a polyphenol and a stilbenoid. It is functionally related to a trans-resveratrol. It is an enantiomer of a (+)-trans-epsilon-viniferin.
target
5-HT Receptor | MAO | Antifection
epsilon-viniferin Preparation Products And Raw materials
Raw materials
Preparation Products
epsilon-viniferin Suppliers
- Tel
- --
- Fax
- --
- info@extrasynthese.com
- Country
- France
- ProdList
- 1333
- Advantage
- 64
- Tel
- --
- Fax
- --
- r.eckert@rothsochiel.fr
- Country
- France
- ProdList
- 2361
- Advantage
- 58
View Lastest Price from epsilon-viniferin manufacturers
- Product
- ε-Viniferin 62218-08-0
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-05-06