BN 50730

Product Name: BN 50730
CAS No.: 132579-32-9
Chemical Name: BN 50730
Synonyms: LAU8080;LAU-8080;BN 50730;LAU 8080;PubChem ID: 3033963;6-(2-Chlorophenyl)-9-((4-methoxyphenyl)thiocarbamoyl)-1-methyl-7,8,9,10-tetrahydro-4H-pyrido(4',3'-4,5)thieno(3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine;4H-Pyrido(4',3'-4,5)thieno(3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine-9(8H)-carbothioamide, 6-(2-chlorophenyl)-7,10-dihydro-N-(4-methoxyphenyl)-1-methyl-
CBNumber: CB91337715
Molecular Formula: C26H23ClN6OS2
Formula Weight: 535.08
MOL File: 132579-32-9.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0009184
Product name: BN-50730
Purity: 95.00%
Packaging: 5MG
Price: $503.79
Updated: 2021/12/16

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BN 50730 Chemical Properties,Usage,Production

Description

Rocepafant, also known as BN-50730; LAU-8080, is a platelet activating factor (PAF) antagonist potentially for the treatment of asthma. BN 50730 attenuates hypoxic-ischemic brain injury in neonatal rats. BN 50730 also showed activity to inhibit tumor necrosis factor-alfa-mediated cytotoxicity on murine L929 tumor cells.

Uses

Rocepafant (BN 50730) is a specific platelet activating factor (PAF) antagonist. Rocepafant can be used in rheumatoid arthritis and nervous system research[1].

References

[1] Silva CL,et al. Formation of a highly stable complex between BN 50730 [tetrahydro-4,7,8,10 methyl-1(chloro-2 phenyl)-6 (methoxy-4 phenyl-carbamoyl)-9 pyrido [4',3'-4,5] thieno [3,2-f] triazolo-1,2,4 [4,3-a] diazepine-1,4] and the platelet-activating factor receptor in rabbit platelet membranes. Biochem Pharmacol. 1996 Jan 26;51(2):193-6. DOI:10.1016/0006-2952(95)02158-2

BN 50730 Preparation Products And Raw materials

Raw materials

Preparation Products

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BN 50730 Suppliers

CHINA 5 United States 1 Global 6

TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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132579-32-9, BN 50730Related Search:

BN 50730

4H-Pyrido(4',3'-4,5)thieno(3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine-9(8H)-carbothioamide, 6-(2-chlorophenyl)-7,10-dihydro-N-(4-methoxyphenyl)-1-methyl-

6-(2-Chlorophenyl)-9-((4-methoxyphenyl)thiocarbamoyl)-1-methyl-7,8,9,10-tetrahydro-4H-pyrido(4',3'-4,5)thieno(3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine

PubChem ID: 3033963

LAU 8080

LAU8080

LAU-8080

132579-32-9