BN 50730
- Product Name
- BN 50730
- CAS No.
- 132579-32-9
- Chemical Name
- BN 50730
- Synonyms
- LAU8080;LAU-8080;BN 50730;LAU 8080;PubChem ID: 3033963;6-(2-Chlorophenyl)-9-((4-methoxyphenyl)thiocarbamoyl)-1-methyl-7,8,9,10-tetrahydro-4H-pyrido(4',3'-4,5)thieno(3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine;4H-Pyrido(4',3'-4,5)thieno(3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine-9(8H)-carbothioamide, 6-(2-chlorophenyl)-7,10-dihydro-N-(4-methoxyphenyl)-1-methyl-
- CBNumber
- CB91337715
- Molecular Formula
- C26H23ClN6OS2
- Formula Weight
- 535.08
- MOL File
- 132579-32-9.mol
N-Bromosuccinimide Price
- Product number
- API0009184
- Product name
- BN-50730
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.79
- Updated
- 2021/12/16
BN 50730 Chemical Properties,Usage,Production
Description
Rocepafant, also known as BN-50730; LAU-8080, is a platelet activating factor (PAF) antagonist potentially for the treatment of asthma. BN 50730 attenuates hypoxic-ischemic brain injury in neonatal rats. BN 50730 also showed activity to inhibit tumor necrosis factor-alfa-mediated cytotoxicity on murine L929 tumor cells.
Uses
Rocepafant (BN 50730) is a specific platelet activating factor (PAF) antagonist. Rocepafant can be used in rheumatoid arthritis and nervous system research[1].
References
[1] Silva CL,et al. Formation of a highly stable complex between BN 50730 [tetrahydro-4,7,8,10 methyl-1(chloro-2 phenyl)-6 (methoxy-4 phenyl-carbamoyl)-9 pyrido [4',3'-4,5] thieno [3,2-f] triazolo-1,2,4 [4,3-a] diazepine-1,4] and the platelet-activating factor receptor in rabbit platelet membranes. Biochem Pharmacol. 1996 Jan 26;51(2):193-6. DOI:10.1016/0006-2952(95)02158-2
BN 50730 Preparation Products And Raw materials
Raw materials
Preparation Products
BN 50730 Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58