ChemicalBook > CAS DataBase List > PD 140376
PD 140376
- Product Name
- PD 140376
- CAS No.
- 149027-97-4
- Chemical Name
- PD 140376
- Synonyms
- PD 140376;[3H]-PD 140376;Benzenebutanoic acid, 4-amino-β-[[(2R)-3-(1H-indol-3-yl)-2-methyl-1-oxo-2-[[(tricyclo[3.3.1.13,7]dec-2-yloxy)carbonyl]amino]propyl]amino]-, (βS)-
- CBNumber
- CB91352387
- Molecular Formula
- C33H40N4O5
- Formula Weight
- 572.71
- MOL File
- 149027-97-4.mol
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PD 140376 Property
- Boiling point:
- 879.8±65.0 °C(Predicted)
- Density
- 1.32±0.1 g/cm3(Predicted)
- pka
- 4.24±0.10(Predicted)
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PD 140376 Chemical Properties,Usage,Production
Description
PD 140376 is a highly selective antagonist radioligand for the cholecystokinin(B)-gastrin receptor in guinea pig cerebral cortex & gastric mucosa in the central and peripheral nervous systems.
Uses
PD 140376 is a potent antagonist for the cholecystokininB/gastrin receptor, with Ki values of 0.18 nM and 0.21 nM in guinea-pig cortex and gastric gland membranes, respectively[1].
References
[1] J C Hunter, et al. [3H]PD 140376: a novel and highly selective antagonist radioligand for the cholecystokininB/gastrin receptor in guinea pig cerebral cortex and gastric mucosa. Mol Pharmacol. 1993 Apr;43(4):595-602 PMID:8474432
PD 140376 Preparation Products And Raw materials
Raw materials
Preparation Products
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PD 140376 Suppliers
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