ChemicalBook > CAS DataBase List > BMY 42393
BMY 42393
- Product Name
- BMY 42393
- CAS No.
- 136451-58-6
- Chemical Name
- BMY 42393
- Synonyms
- BMY 42393;Acetic acid, 2-[3-[2-(4,5-diphenyl-2-oxazolyl)ethyl]phenoxy]-
- CBNumber
- CB91364773
- Molecular Formula
- C25H21NO4
- Formula Weight
- 399.44
- MOL File
- 136451-58-6.mol
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BMY 42393 Property
- Boiling point:
- 579.9±50.0 °C(Predicted)
- Density
- 1.230±0.06 g/cm3(Predicted)
- pka
- 3.18±0.10(Predicted)
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BMY 42393 Chemical Properties,Usage,Production
Description
BMY-42393 is orally active and selective platelet aggregation inhibitor. BMY-42393 is also a prostacyclin partial agonist that inhibited ADP, collagen and thrombin-induced platelet aggregation (IC50 range 0.3 - 2.0 microM). BMY-42393 stimulated platelet adenylate cyclase activity (EC50 = 25 nM). Platelets treated with BMY 42393 showed an elevation of cAMP levels and activation of cAMP-dependent protein kinase. BMY 42393 also inhibited thrombin-induced elevation of intracellular free calcium. BMY 42393 competed for radiolabeled iloprost and PGE1 binding to platelet membranes (IC50; 170 nM and 130 nM, respectively).
BMY 42393 Preparation Products And Raw materials
Raw materials
Preparation Products
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BMY 42393 Suppliers
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 19699
- Advantage
- 58
- Tel
- +8613564774135
- zijue.cai@tsbiochem.com
- Country
- United States
- ProdList
- 19881
- Advantage
- 58