eckol

Product Name: eckol
CAS No.: 88798-74-7
Chemical Name: eckol
Synonyms: eckol;Acanthol;4-(3,5-Dihydroxyphenoxy)dibenzo-p-dioxin-1,3,6,8-tetrol;1-(Resorcinol-5-yloxy)-2,4,7,9-tetrahydroxydibenzo-p-dioxin;4-(3,5-Dihydroxyphenoxy)dibenzo[b,e][1,4]dioxin-1,3,6,8-tetrol;Dibenzo[b,e][1,4]dioxin-1,3,6,8-tetrol, 4-(3,5-dihydroxyphenoxy)-
CBNumber: CB91370006
Molecular Formula: C18H12O9
Formula Weight: 372.28
MOL File: 88798-74-7.mol

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eckol Property

Melting point:: 243-244 °C
Boiling point:: 685.5±55.0 °C(Predicted)
Density: 1.778±0.06 g/cm3(Predicted)
pka: 8.06±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: E325900
Product name: Eckol
Packaging: 1mg
Price: $185
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0019459
Product name: ECKOL
Purity: 95.00%
Packaging: 5MG
Price: $495.3
Updated: 2021/12/16

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eckol Chemical Properties,Usage,Production

Uses

Eckol is a polyphenolic compound that can be used as a potential drug candidate for treatment of Alzheimer''s disease. Eckol also enhances heme oxygenase-1 expression through activation of Nrf2/JNK pathway in HepG2 cells.

Definition

ChEBI: A phlorotannin that is oxanthrene-1,3,6,8-tetrol substituted by a 3,5-dihydroxyphenoxy moiety at position 4. Isolated from the marine brown alga, Ecklonia cava, it exhibits antioxidant activity.

in vivo

Foliar application of Eckol (1 μM) significantly enhanced shoot and root length, shoot and root fresh and dry weight, leaf area and leaf number^[2].
Eckol (50 or 100 μg/mouse; intradermal; once) reduces allergic inflammatory responses in the passive cutaneous anaphylaxis (PCA)-induced mice^[3].

Animal Model:	BALB/c mice (8 weeks old), IgE/BSA-induced passive cutaneous anaphylaxis (PCA) model^[3]
Dosage:	50 or 100 μg/mouse
Administration:	Intradermal injection, applied on mice ear 2 h prior to anaphylaxis induction
Result:	Reduced allergic inflammatory responses.

IC 50

hMAO-A: 7.20 μM (IC₅₀); hMAO-B: 83.44 μM (IC₅₀); H1N1: 89.5 μM (IC₅₀)

eckol Preparation Products And Raw materials

Raw materials

Preparation Products

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eckol Suppliers

China 6 India 1 United States 1 Global 8

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Aktin Chemicals, Inc.

Tel: 028-85159085
Email: info@aktinchem.com
Country: China
ProdList: 1860
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29423
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Henan Tianfu Chemical Co.,Ltd.

Tel: +86-0371-55170693 +86-19937530512
Fax: 0371-55170693
Email: info@tianfuchem.com
Country: China
ProdList: 21612
Advantage: 55

Shanghai Likang New Materials Co., Limited

Tel: +86-16631818819 +86-17736933208
Email: 3684455296@qq.com
Country: China
ProdList: 9300
Advantage: 58

88798-74-7, eckolRelated Search:

DIBENZO-P-DIOXIN eckol

eckol

1-(Resorcinol-5-yloxy)-2,4,7,9-tetrahydroxydibenzo-p-dioxin

4-(3,5-Dihydroxyphenoxy)dibenzo[b,e][1,4]dioxin-1,3,6,8-tetrol

4-(3,5-Dihydroxyphenoxy)dibenzo-p-dioxin-1,3,6,8-tetrol

Dibenzo[b,e][1,4]dioxin-1,3,6,8-tetrol, 4-(3,5-dihydroxyphenoxy)-

Acanthol

88798-74-7