ChemicalBook > CAS DataBase List > AK 295
AK 295
- Product Name
- AK 295
- CAS No.
- 160399-35-9
- Chemical Name
- AK 295
- Synonyms
- CX295;CX-295;CX 295;Carbamic acid, N-[(1S)-1-[[[1-ethyl-3-[[3-(4-morpholinyl)propyl]amino]-2,3-dioxopropyl]amino]carbonyl]-3-methylbutyl]-, phenylmethyl ester
- CBNumber
- CB91376750
- Molecular Formula
- C26H40N4O6
- Formula Weight
- 504.62
- MOL File
- 160399-35-9.mol
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AK 295 Property
- form
- Solid
- color
- White to off-white
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AK 295 Chemical Properties,Usage,Production
Description
AK 295, also known asCX 295, is a dipeptide alpha-ketoamide calpain inhibitor.
Uses
AK 295 (CX 295) is a calpain inhibitor that inhibits apoptosis through a calpain-dependent pathway. AK 295 improves neurological function in a rat model of spinal cord injury (SCI). AK 295 can be used in the study of neurodegenerative diseases, such as bulbar amyotrophy, stroke, Alzheimer's disease, Parkinson's disease, multiple sclerosis[1].
References
[1] Colak A, et al. Calpain inhibitor AK 295 inhibits calpain-induced apoptosis and improves neurologic function after traumatic spinal cord injury in rats. Neurocirugia (Astur). 2009 Jun;20(3):245-54. PMID:19575128
AK 295 Preparation Products And Raw materials
Raw materials
Preparation Products
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AK 295 Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 29496
- Advantage
- 58