glycyl-glycyl-cysteine

Product Name: glycyl-glycyl-cysteine
CAS No.: 95416-30-1
Chemical Name: glycyl-glycyl-cysteine
Synonyms: Gly-Gly-Cys;Gly-Gly-L-Cys;glycyl-glycyl-cysteine;L-Cysteine, glycylglycyl-;(2R)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-sulfanylpropanoic acid
CBNumber: CB91378284
Molecular Formula: C7H13N3O4S
Formula Weight: 235.26
MOL File: 95416-30-1.mol

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glycyl-glycyl-cysteine Property

pka: pK1:2.71;pK2:2.71;pK3:7.94;pK4:7.94 (35°C)
Sequence: H-Gly-Gly-Cys-OH

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Hazard and Precautionary Statements (GHS)

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glycyl-glycyl-cysteine Chemical Properties,Usage,Production

Uses

Glycylglycylcysteine is a Thrombin Activatable Fibrinolysis Inhibitor (TAFI) inhibitor with a Ki of 0.99 μM and a IC50 of 9.4 μM in TAFI substrate assays. TAFI is a basic carboxypeptidase that functions as a fibrinolysis inhibitor through the cleavage of C-terminal lysine on partially degraded fibrin[1].

Definition

ChEBI: Gly-Gly-Cys is an oligopeptide.

References

[1] Do YH, et al. Inhibition of thrombin activatable fibrinolysis inhibitor by cysteine derivatives. Thromb Res. 2005;116(3):265-71. DOI:10.1016/j.thromres.2004.12.023

glycyl-glycyl-cysteine Preparation Products And Raw materials

Raw materials

Preparation Products

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glycyl-glycyl-cysteine Suppliers

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95416-30-1, glycyl-glycyl-cysteineRelated Search:

H-GLY-GLY-GLU-ALA-OH H-GLY-GLY-ASP-ALA-OH H-GLY-GLY-PRO-ALA-OH H-GLY-GLY-SAR-OH H-GLY-GLY-GLU-OH Gly-Gly-Leu H-GLY-GLY-MET-OH H-Gly-Gly-Lys-Ala-Ala-OH Glycylglycyl-L-isoleucine H-GLY-GLY-HIS-ALA-OH glycyl-glycyl-proline H-GLY-GLY-GLN-OH H-GLY-GLY-TRP-OH H-Gly-Gly-Lys-OH

glycyl-glycyl-cysteine

Gly-Gly-L-Cys

L-Cysteine, glycylglycyl-

(2R)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-sulfanylpropanoic acid

Gly-Gly-Cys

95416-30-1