1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide
- Product Name
- 1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide
- CAS No.
- 15580-20-8
- Chemical Name
- 1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide
- Synonyms
- NSC 163986;1-Cyclohexyl-3-(2-morpholinoethyl)carbodiimide;N-(2-Morpholinoethyl)cyclohexanecarboximidamide;N-Cyclohexyl-N'-beta-morpholinoethylcarbodiimide;Cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide;1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide;4-Morpholineethanamine,N-(cyclohexylcarbonimidoyl)-;N-cyclohexyl-N'-(2-(4-morpholinyl)ethyl)carbodiimide;N'-cyclohexyl-N-(2-morpholin-4-ylethyl)methanediimine;N-(((2-Morpholinoethyl)imino)methylene)cyclohexanamine
- CBNumber
- CB91378714
- Molecular Formula
- C13H23N3O
- Formula Weight
- 237.34
- MOL File
- 15580-20-8.mol
1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide Property
- Boiling point:
- 145 °C(Press: 0.2 Torr)
- Density
- 1.12±0.1 g/cm3(Predicted)
- solubility
- soluble in DMF, CH2Cl2, dioxane, xylene.
- pka
- 6.90±0.10(Predicted)
N-Bromosuccinimide Price
- Product number
- C992350
- Product name
- 1-Cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide
- Packaging
- 10mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- FC64700
- Product name
- 1-Cyclohexyl-3-(2-(4-Morpholinyl)Ethyl)Carbodiimide
- Packaging
- 50mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- FC64700
- Product name
- 1-Cyclohexyl-3-(2-(4-Morpholinyl)Ethyl)Carbodiimide
- Packaging
- 100mg
- Price
- $400
- Updated
- 2021/12/16
- Product number
- CHM0297012
- Product name
- 1-CYCLOHEXYL-3-(2-(4-MORPHOLINYL)ETHYL)CARBODIIMIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.06
- Updated
- 2021/12/16
- Product number
- FC64700
- Product name
- 1-Cyclohexyl-3-(2-(4-Morpholinyl)Ethyl)Carbodiimide
- Packaging
- 250mg
- Price
- $600
- Updated
- 2021/12/16
1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide Chemical Properties,Usage,Production
Uses
1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide is a coupling agent for peptide synthesis; used to make sulfate esters from alcohols.
Definition
ChEBI: A carbodiimide having cyclcohexyl and 2-(4-morpholinyl)ethyl as the two N-substituents.
Synthesis Reference(s)
Synthesis, p. 520, 1987 DOI: 10.1055/s-1987-27992
Synthesis
The Preparative Methods of 1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide: from cyclohexyl isothiocyanate and N-(2-aminoethyl)morpholine (67% yield) by dehydration of the corresponding urea with p-Toluenesulfonyl Chloride, Potassium Carbonate, and Benzyltriethylammonium Chloride (91% yield); or by the reaction of cyclohexyl isocyanate, 2-(4-morpholinyl)ethyl diethylphosphoramidate, and potassium carbonate (82% yield).
References
1. For general reviews on the use of carbodiimides, see (a) Kurzer, F.; Douraghi-Zadeh, K. CRV 1967, 67, 107. (b) Williams, A.; Ibrahim, I. T. CRV 1981, 81, 589. (c) Mikolajczyk, M.; Kielbasinski, P. T 1981, 37, 233.
2. Sheehan, J. C.; Hlavka, J. J. JOC 1956, 21, 439.
3. Jászay, Z. M.; Petneházy, I.; T?ke, L.; Szajáni, B. S 1987, 520.
4. Jászay, Z. M.; Petneházy, I.; T?ke, L.; Szajáni, B. S 1988, 397.
1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide manufacturers
- Product
- 1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide 15580-20-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-09-26
- Product
- 1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide 15580-20-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimide 15580-20-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08