SR 11237

Product Name: SR 11237
CAS No.: 146670-40-8
Chemical Name: SR 11237
Synonyms: BMS649;SR 11237;BMS 188649;SR11237, 10 mM in DMSO;4-(2-(5,5,8,8-tetraMethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-dioxolan-2-yl)benzoic acid;4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dioxolan-2-yl]-benzoicacid;Benzoic acid, 4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dioxolan-2-yl]-;Retinoid X receptors,bone,BMS 649,transactivate,BMS649,Retinoic acid receptors,reporter,ossification,RAR/RXR,inhibit,Inhibitor,RXR/RXR,BMS-649,SR11237,homodimers,gene,SR-11237
CBNumber: CB91379089
Molecular Formula: C24H28O4
Formula Weight: 380.48
MOL File: 146670-40-8.mol

More

Less

SR 11237 Property

storage temp.: Store at -20°C
solubility: DMSO: >28mg/mL (warmed)
form: powder
color: white to off-white

More

Less

Safety

WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S8951
Product name: SR11237
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $137
Updated: 2025/07/31

Sigma-Aldrich

Product number: S8951
Product name: SR11237
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $530
Updated: 2025/07/31

Tocris

Product number: 3411
Product name: SR11237
Purity: ≥98%(HPLC)
Packaging: 10
Price: $207
Updated: 2021/12/16

Tocris

Product number: 3411
Product name: SR11237
Purity: ≥98%(HPLC)
Packaging: 50
Price: $852
Updated: 2021/12/16

TRC

Product number: S684463
Product name: SR11237
Packaging: 25mg
Price: $310
Updated: 2021/12/16

More

Less

SR 11237 Chemical Properties,Usage,Production

Uses

SR 11237 is a pan RXR agonist with without RAR activity. It is used in treatment of neurodegenerative diseases.

Biological Activity

Pan retinoid X receptor (RXR) agonist that is devoid of any RAR activity.

in vivo

SR11237 (BMS-649) (25 mg/kg; i.p.; daily from post-natal days 5 to 15) causes irregular ossification and premature closure of the growth plate^[2].

Animal Model:	Sprague-Dawley rats^[2]
Dosage:	25 mg/kg
Administration:	I.p.; daily from post-natal days 5 to 15
Result:	Caused disturbed ossification and bone morphology in rats, including premature growth plate closure and infiltration of ossified tissue through the central epiphysis.

storage

Store at -20°C

SR 11237 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

SR 11237 Suppliers

China 55 South Korea 1 United Kingdom 1 United States 7 Global 64

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4757
Advantage: 55

Shanghaizehan biopharma technology co., Ltd.

Tel: 021-61350663 13052117465
Fax: 021-61350662
Email: sales@zehanbiopharma.com
Country: China
ProdList: 984
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai Rechem science Co., Ltd.

Tel: 021-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2990
Advantage: 58

Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 12476
Advantage: 58

Taizhou Crene Biotechnology Co. Ltd.

Tel: +86-0576-88813233 +86-13396860566
Email: sales@pharm-intermediates.com
Country: China
ProdList: 1991
Advantage: 58

146670-40-8, SR 11237Related Search:

SR 11237

4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dioxolan-2-yl]-benzoicacid

4-(2-(5,5,8,8-tetraMethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-dioxolan-2-yl)benzoic acid

BMS 188649

BMS649

Benzoic acid, 4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dioxolan-2-yl]-

Retinoid X receptors,bone,BMS 649,transactivate,BMS649,Retinoic acid receptors,reporter,ossification,RAR/RXR,inhibit,Inhibitor,RXR/RXR,BMS-649,SR11237,homodimers,gene,SR-11237

SR11237, 10 mM in DMSO

146670-40-8