1-(2-chloro-4-hydroxyphenyl)-tert-butylaminoethanol

Product Name: 1-(2-chloro-4-hydroxyphenyl)-tert-butylaminoethanol
CAS No.: 58020-43-2
Chemical Name: 1-(2-chloro-4-hydroxyphenyl)-tert-butylaminoethanol
Synonyms: HOKU 81;4-Hydroxytulobuterol;4-HYDROXYTULOBUTEROL; HOKU 81; HOKU81;1-(2-chloro-4-hydroxyphenyl)-tert-butylaminoethanol;2-Chloro-α-[(tert-butylamino)methyl]-4-hydroxybenzenemethanol;Benzenemethanol,2-chloro-a-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-;Benzenemethanol, 2-chloro-α-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-;2-Chloro-alpha-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxybenzenemethanol
CBNumber: CB91381657
Molecular Formula: C12H18ClNO2
Formula Weight: 243.73
MOL File: 58020-43-2.mol

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1-(2-chloro-4-hydroxyphenyl)-tert-butylaminoethanol Property

storage temp.: Store at -20°C
solubility: DMSO : 50 mg/mL (205.15 mM; Need ultrasonic)
form: Powder
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0858
Product name: HOKU-81
Packaging: 5mg
Price: $120
Updated: 2021/12/16

ApexBio Technology

Product number: A3477
Product name: HOKU-81
Packaging: 5mg
Price: $173
Updated: 2021/12/16

ChemScene

Product number: CS-0858
Product name: HOKU-81
Packaging: 25mg
Price: $462
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0123013
Product name: 1-(2-CHLORO-4-HYDROXYPHENYL)-TERT-BUTYLAMINOETHANOL
Purity: 95.00%
Packaging: 5MG
Price: $505.87
Updated: 2021/12/16

ApexBio Technology

Product number: A3477
Product name: HOKU-81
Packaging: 25mg
Price: $693
Updated: 2021/12/16

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1-(2-chloro-4-hydroxyphenyl)-tert-butylaminoethanol Chemical Properties,Usage,Production

Uses

HOKU-81 (4-Hydroxytulobuterol) is one of the metabolites of Tulobuterol (HY-B1810). HOKU-81 is a potent and selective β2-adrenoceptor stimulant. HOKU-81 has bronchodilating effect[1][2].

IC 50

Beta-2 adrenergic receptor

References

[1] Kubo S, Matsubara I, Yamazaki M et al. Pharmacological studies of 1-(2-chloro-4-hydroxyphenyl)-2-t-butylaminoethanol (HOKU-81), a new bronchodilator. 1st Communication: Bronchodilator and cardiovascular actions. Arzneimittelforschung. 1980;30(8):1272-8. PMID:7192141
[2] Gomi Y, Shirahase H, Funato H. Effects of 1-(2-chloro-4-hydroxyphenyl)-t-butylaminoethanol (HOKU-81), a new bronchodilator, on isolated trachea and atria of guinea pig. Jpn J Pharmacol. 1979 Aug;29(4):515-24. DOI:10.1254/jjp.29.515

1-(2-chloro-4-hydroxyphenyl)-tert-butylaminoethanol Preparation Products And Raw materials

Raw materials

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1-(2-chloro-4-hydroxyphenyl)-tert-butylaminoethanol Suppliers

China 42 Switzerland 1 United States 7 Global 50

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