chaetomellic acid A

Product Name: chaetomellic acid A
CAS No.: 148796-51-4
Chemical Name: chaetomellic acid A
Synonyms: chaetomellic acid A;2-Butenedioic acid, 2-methyl-3-tetradecyl-, (2Z)-;Chaetomellic acid A, farnesyltransferase inhibitor
CBNumber: CB91391645
Molecular Formula: C19H34O4
Formula Weight: 326.47
MOL File: 148796-51-4.mol

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chaetomellic acid A Property

form: White to off-white solid.

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Hazard and Precautionary Statements (GHS)

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chaetomellic acid A Chemical Properties,Usage,Production

Uses

Chaetomellic acid A can be isolated from Chaetomella acutiseta. Chaetomellic acid A is a specific inhibitor of farnesyl-protein transferase. Chaetomellic acid A decreases oxidative stress-induced apoptosis in cells. Chaetomellic acid A reduces renal damage after unilateral ureteral obstruction (UUO) in mice[1][2].

References

[1] Nogueira A, et al. The Effects of Long-Term Chaetomellic Acid A Administration on Renal Function and Oxidative Stress in a Rat Model of Renal Mass Reduction. Biomed Res Int. 2017;2017:5125980. DOI:10.1155/2017/5125980
[2] Lingham RB, et al. Chaetomella acutiseta produces chaetomellic acids A and B which are reversible inhibitors of farnesyl-protein transferase. Appl Microbiol Biotechnol. 1993 Nov;40(2-3):370-4. DOI:10.1007/BF00170395

chaetomellic acid A Preparation Products And Raw materials

Raw materials

Preparation Products

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chaetomellic acid A Suppliers

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148796-51-4, chaetomellic acid ARelated Search:

B581 L-744,832 ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID

chaetomellic acid A

2-Butenedioic acid, 2-methyl-3-tetradecyl-, (2Z)-

Chaetomellic acid A, farnesyltransferase inhibitor

148796-51-4