ChemicalBook > CAS DataBase List > Chebulinic acid

Chebulinic acid

Product Name
Chebulinic acid
CAS No.
18942-26-2
Chemical Name
Chebulinic acid
Synonyms
Eutannin;NSC69862;CHEBULINIC ACID;Chebulinic acid-RM;CHEBULINIC ACID(SH);CHEBULINIC ACID USP/EP/BP;Chebulinic acid, 10 mM in DMSO;Chebulinic acid >=85% (LC/MS-ELSD);b-D-Glucopyranose,1,3,6-tris(3,4,5-trihydroxybenzoate), cyclic 22:41-ester with (2S)-[(3R,4S)-5-carboxy-3,4-dihydro-3,7,8-trihydroxy-2-oxo-2H-1-benzopyran-4-yl]butanedioicacid;β-D-Glucopyranose, 1,3,6-tris(3,4,5-trihydroxybenzoate), cyclic 2→2:4→1-ester with (2S)-[(3R,4S)-5-carboxy-3,4-dihydro-3,7,8-trihydroxy-2-oxo-2H-1-benzopyran-4-yl]butanedioic acid
CBNumber
CB9139286
Molecular Formula
C41H32O27
Formula Weight
956.68
MOL File
18942-26-2.mol
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Chebulinic acid Property

Boiling point:
1460.0±65.0 °C(Predicted)
Density 
2.04
storage temp. 
-20°C
solubility 
Soluble in acetone, methanol and hot water; insoluble in chloroform and n-hexane
form 
powder
pka
4.14±0.10(Predicted)
color 
Beige
InChIKey
YGVHOSGNOYKRIH-KOPSEHRPNA-N
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00271
Product name
Chebulinic acid
Purity
≥85% (LC/MS-ELSD)
Packaging
1mg
Price
$485
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL80572
Product name
Chebulinic acid
Purity
phyproof? Reference Substance
Packaging
10mg
Price
$1040
Updated
2024/03/01
Sigma-Aldrich
Product number
40820
Product name
Chebulinic acid
Purity
analytical standard
Packaging
10mg
Price
$855
Updated
2024/03/01
Usbiological
Product number
300064
Product name
Chebulinic acid
Packaging
10mg
Price
$632
Updated
2021/12/16
TRC
Product number
C291895
Product name
Chebulinic acid
Packaging
5mg
Price
$400
Updated
2021/12/16
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Chebulinic acid Chemical Properties,Usage,Production

Uses

Chebulinic Acid has been shown to prevent epithelial mesenchymal transition in retinal pigment epithelial cells through inhibition of SMAD-3 phosphorylation. This prevents retinal detachment in the process of proliferative vitreoretinopathy.

Definition

ChEBI: Chebulinic acid is a tannin.

Origin

Chebulinic acid, an ellagitannin found commonly in Terminalia chebula, has been used extensively to treat diverse eras of ailments traditionally. It was also present in Phyllanthus emblica, Dimocarpus longan, Terminalia catappa, Terminalia parviflora, Terminalia macroptera, Lumnttzera racemosa, and Dendrophthoe falcate and has been used extensively in the traditional Indian system of medicine. It was first isolated by Fridolin in the year 1884[1].

Biological Activity

Chebulinic acid is polyphenol th at has shown antihypertensive, and anti-oxidant properties. Its antihypertensive effects may be due to decreased cardiac output from reduced left ventricular contraction.

Chebulinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Chebulinic acid manufacturers

Career Henan Chemical Co
Product
CHEBULINIC ACID 18942-26-2
Price
US $8.00/KG
Min. Order
1g
Purity
>98% HPLC
Supply Ability
kg---ton
Release date
2020-02-20

18942-26-2, Chebulinic acidRelated Search:


  • CHEBULINIC ACID
  • NSC69862
  • CHEBULINIC ACID(SH)
  • Eutannin
  • β-D-Glucopyranose, 1,3,6-tris(3,4,5-trihydroxybenzoate), cyclic 2→2:4→1-ester with (2S)-[(3R,4S)-5-carboxy-3,4-dihydro-3,7,8-trihydroxy-2-oxo-2H-1-benzopyran-4-yl]butanedioic acid
  • b-D-Glucopyranose,1,3,6-tris(3,4,5-trihydroxybenzoate), cyclic 22:41-ester with (2S)-[(3R,4S)-5-carboxy-3,4-dihydro-3,7,8-trihydroxy-2-oxo-2H-1-benzopyran-4-yl]butanedioicacid
  • Chebulinic acid >=85% (LC/MS-ELSD)
  • CHEBULINIC ACID USP/EP/BP
  • 2-((3R,3aS,4S,7R,8R,10S,11R,17R)-3,15,16-Trihydroxy-2,5,13-trioxo-10,17-bis((3,4,5-trihydroxybenzoyl)oxy)-8-(((3,4,5-trihydroxybenzoyl)oxy)methyl)-2,3,3a,4,5,7,8,10,11,13-decahydro-7,11-methano[1,4,7]trioxacyclotridecino[11,10,9-de]chromen-4-yl)acetic acid
  • Chebulinic acid-RM
  • Chebulinic acid, 10 mM in DMSO
  • 18942-26-2
  • C41H34O28
  • C41H32O27