ChemicalBook > CAS DataBase List > MDL 72527
MDL 72527
- Product Name
- MDL 72527
- CAS No.
- 93565-01-6
- Chemical Name
- MDL 72527
- Synonyms
- CPC-200;MDL 72527;MDL727527;Mdl-72527da;MDL 72527, >=97%;MDL 72527【M2949】;MDL-72527 (MDL72527;MDL 72527, 10 mM in DMSO;MDL 72527 (hydrochloride);N1,N4-Bis(2,3-butadienyl)putrescine
- CBNumber
- CB91394040
- Molecular Formula
- C12H20N2.2HCl
- Formula Weight
- 0
- MOL File
- 93565-01-6.mol
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MDL 72527 Property
- Melting point:
- 236-237 °C (decomp)(Solv: ethanol (64-17-5); ethyl acetate (141-78-6))
- storage temp.
- Sealed in dry,2-8°C
- solubility
- H2O: soluble15mg/mL, clear
- form
- powder
- color
- light yellow to light brown
- Water Solubility
- H2O: 15mg/mL, clear
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- M2949
- Product name
- MDL 72527
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $121
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- M2949
- Product name
- MDL 72527
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $485.38
- Updated
- 2025/07/31
Cayman Chemical
- Product number
- 13996
- Product name
- MDL 72527 (hydrochloride)
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $37
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 13996
- Product name
- MDL 72527 (hydrochloride)
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $116
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 13996
- Product name
- MDL 72527 (hydrochloride)
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $178
- Updated
- 2024/03/01
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MDL 72527 Chemical Properties,Usage,Production
Uses
MDL 72527 is a lysosomotropic polyamineoxidase inhibitor.
Biological Activity
Polyamine oxidase (POA) inhibitor. Does not inhibit monoamine oxidase or D-Amino acid oxidase. Displays anticancer and neuroprotective activity in vivo .
in vivo
MDL 72527 (100 mg/kg; i.p.; once) shows neuroprotective against neuronal cell damage after temporary focal cerebral ischemia[1].
| Animal Model: | 250-300 g, Male spontaneously hypertensive rats (SHRs)[1] |
| Dosage: | 100 mg/kg |
| Administration: | I.p.; after the induction of ischemia |
| Result: | Significantly reduced meanarterial blood pressure, changed the brain edema formation from 85.7 ± 0.3 to 84.5 ± 0.9% in cortex and from 79.9 ± 1.7 to 78.4 ± 2.0% in subcortex (difference not significant), reduced ischemic injury volume by 22% in the cortex and 17% in the subcortex. |
MDL 72527 Preparation Products And Raw materials
Raw materials
Preparation Products
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