kerasin
- Product Name
- kerasin
- CAS No.
- 536-13-0
- Chemical Name
- kerasin
- Synonyms
- Cerasine;Galactosylceramides (non-hydroxy);Galactosylcerebrosides (non-hydroxy);Galactosylceramide (non-hydroxy) (bovine);N-[(1R,2S,E)-1-[(β-D-Galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]tetracosanamide
- CBNumber
- CB91396327
- Molecular Formula
- C48H91NO8
- Formula Weight
- 810.23804
- MOL File
- 536-13-0.mol
kerasin Property
- storage temp.
- Store at -20°C
- solubility
- CHCl3:CH3OH:H2O (3:2:1): Soluble
- form
- A solid
N-Bromosuccinimide Price
- Product number
- 24835
- Product name
- Galactosylcerebrosides (non-hydroxy)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $43
- Updated
- 2024/03/01
- Product number
- 24835
- Product name
- Galactosylceramides (non-hydroxy)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $209
- Updated
- 2024/03/01
- Product number
- 24835
- Product name
- Galactosylcerebrosides (non-hydroxy)
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $25
- Updated
- 2021/12/16
- Product number
- 24835
- Product name
- Galactosylcerebrosides (non-hydroxy)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $116
- Updated
- 2024/03/01
kerasin Chemical Properties,Usage,Production
Description
Galactosylceramides are glycosphingolipids that contain galactose attached to a ceramide containing an N-acyl hydroxy or non-hydroxy fatty acid. They are metabolic precursors to sulfatide , found primarily in nerve tissues, and are the main glycosphingolipids in the central nervous system.1,2 Galactosylceramides are involved in a multitude of cellular processes including cell agglutination, cellular signaling in glycosynapses, cellular development, and activation of T cells.1,2,3 They accumulate in globoid cells in the brain of patients with Krabbe disease, a disorder characterized by a deficiency in galactosylcerebrosidase activity.2 This product contains non-hydroxy galactosylceramides with primarily C24:0 and C24:1 fatty acyl chain lengths. As this product is derived from a natural source, there may be variations in the sphingoid backbone.
Definition
ChEBI: Beta-D-galactosyl-N-(tetracosanoyl)sphingosine is a N-acyl-beta-D-galactosylsphingosine in which the acyl group is tetracosananoyl. It has a role as a mouse metabolite. It is functionally related to a tetracosanoic acid.
References
1. Boggs, J.M., Gao, W., Zhao, J., et al. Participation of galactosylceramide and sulfatide in glycosynapses between oligodendrocyte or myelin membranes FEBS Lett. 584(9),1771-1778(2010).
2. Wenger, D.A., Rafi, M.A., and Luzi, P. Krabbe disease: One hundred years from the bedside to the bench to the bedside J. Neurosci. Res. 94(11),982-989(2016).
3. Birkholz, A.M., Howell, A.R., and Kronenberg, M. The α and Ω of galactosylceramides in T cell immune function J. Biol. Chem. 290(25),15365-15370(2015).
kerasin Preparation Products And Raw materials
Raw materials
Preparation Products
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