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Monomethyl succinate

Product Name
Monomethyl succinate
CAS No.
77341-67-4
Chemical Name
Monomethyl succinate
Synonyms
Monomethyl succinate;Mononmethyl succinate;MONO-MENTHYLSUCCINATE;(-)-Menthyl Succinate;(-)-MenthylSuccinate>Succinic Acid (-)-Menthyl Ester;Succinic acid menthol monoester;(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Succinate;Butanedioic acid mono-(5-methyl-2-isopropyl-cyclohexyl) ester;Succinic Acid (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Ester
CBNumber
CB91424891
Molecular Formula
C14H24O4
Formula Weight
256.34
MOL File
77341-67-4.mol
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Monomethyl succinate Property

Melting point:
62.0 to 66.0 °C
Boiling point:
374.3±25.0 °C(Predicted)
Density 
1.06±0.1 g/cm3(Predicted)
FEMA 
3810 | MONO-MENTHYL SUCCINATE
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
4.42±0.17(Predicted)
color 
White to Almost white
Odor
at 100.00 %. odorless
Odor Type
odorless
JECFA Number
447
LogP
4.35
EPA Substance Registry System
Butanedioic acid, 1-[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl] ester (77341-67-4)
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Safety

HS Code 
2917.19.7050
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2482
Product name
(-)-Menthyl Succinate
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$101
Updated
2025/07/31
Matrix Scientific
Product number
096892
Product name
4-(((1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl)-oxy)-4-oxobutanoic acid
Purity
95+%
Packaging
5g
Price
$60
Updated
2021/12/16
Chem-Impex
Product number
39229
Product name
(-)-Menthylsuccinate,98%(Assaybytitration,GC)
Purity
98%(Assaybytitration,GC)
Packaging
25G
Price
$98.56
Updated
2021/12/16
Matrix Scientific
Product number
096892
Product name
4-(((1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl)-oxy)-4-oxobutanoic acid
Purity
95+%
Packaging
10g
Price
$100
Updated
2021/12/16
Matrix Scientific
Product number
096892
Product name
4-(((1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl)-oxy)-4-oxobutanoic acid
Purity
95+%
Packaging
1g
Price
$19
Updated
2021/12/16
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Monomethyl succinate Chemical Properties,Usage,Production

Chemical Properties

mono-Menthyl succinate has a mint, cooling taste.

Uses

Mono-methyl Succinate is one of the substances used in the study of lactobacillus plantarum culture supernatants with potential pro-heating and anti-pathogenic properties in skin chronic wounds

Aroma threshold values

Aroma characteristics at 1.0%: little or no apparent aroma.

Taste threshold values

Threshold in water: 40 ppm. Taste characteristics at 100 ppm: lingering cooling with a slightly oily mouthfeel.

Synthesis Reference(s)

The Journal of Organic Chemistry, 51, p. 2039, 1986 DOI: 10.1021/jo00361a019

Synthesis

108-30-5

2216-51-5

77341-67-4

Synthesis Example 1: Synthesis of 1-menthyl-(1-menthoxyethyl) succinate Synthesis of Compound 1: To a 100 mL autoclave, 10.00 g (63.99 mmol) of L-menthol and 6.40 g (63.96 mmol) of succinic anhydride were added, and the air in the autoclave was replaced with nitrogen. Subsequently, the mixture was stirred at 110°C for 8 hours. After completion of the reaction, it was cooled to room temperature and 100 mL of hexane was added to the reaction mixture. The precipitated crystals were filtered and the hexane phase of the filtrate was concentrated to give 16.61 g of 1-menthylsuccinic acid with purity >99.9%.

References

[1] Patent: US2011/81393, 2011, A1. Location in patent: Page/Page column 10
[2] Molecules, 2005, vol. 10, # 1, p. 81 - 97
[3] Molecular Crystals and Liquid Crystals, 2015, vol. 609, # 1, p. 31 - 39
[4] Patent: US2009/28803, 2009, A1

Monomethyl succinate Preparation Products And Raw materials

Raw materials

Preparation Products

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Monomethyl succinate Suppliers

TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
Triveni chemicals
Tel
--
Fax
--
Email
sales@trivenichemical.com
Country
India
ProdList
6088
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from Monomethyl succinate manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
Monomethyl succinate 77341-67-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99.00%
Supply Ability
20tons
Release date
2023-09-14
JINING XINHE CHEMICAL CO., LTD
Product
Monomethyl succinate 77341-67-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10ton
Release date
2024-07-22
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]oxy-4-oxobutanoic acid 77341-67-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26

77341-67-4, Monomethyl succinateRelated Search:


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  • Monomethyl succinate
  • Mononmethyl succinate
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  • (-)-MenthylSuccinate&gt
  • Butanedioic acid, 1-[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl] ester
  • (-)-Menthyl Succinate
  • (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Succinate
  • Succinic Acid (-)-Menthyl Ester
  • Succinic Acid (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Ester
  • Succinic acid menthol monoester
  • 4-[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]oxy-4-oxobutanoicaci
  • [1R-(1-α,2β,5α)]-mono[5-methyl-2-(1-methylethyl)cyclohexyl]butanedioate
  • 77341-67-4