ChemicalBook > CAS DataBase List > Platelet Activating Factor-16

Platelet Activating Factor-16

Product Name
Platelet Activating Factor-16
CAS No.
74389-68-7
Chemical Name
Platelet Activating Factor-16
Synonyms
PAF;C16PAF;ACGEPC;PAF (C16);C16-02:0 PC;PAF (C16),99%;C16-PAF-acether;C16-PAF(PAF (C16));C16 ENANTIOMERIC PAF;Rabbit Anti-PAF antibody
CBNumber
CB9143348
Molecular Formula
C26H54NO7P
Formula Weight
523.68
MOL File
74389-68-7.mol
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Platelet Activating Factor-16 Property

Melting point:
247 °C
storage temp. 
-20°C
solubility 
Soluble in H2O or ethanol
form 
lyophilized powder
color 
White to off-white
Water Solubility 
Soluble to 100 mM in water
BRN 
3574588
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Safety

Hazard Codes 
Xn
Risk Statements 
22-38-40-48/20/22
Safety Statements 
36/37-24/25-22
RIDADR 
UN 1888 6.1/PG 3
WGK Germany 
3
RTECS 
EC6060000
F 
10-21
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
511075
Product name
Platelet Activating Factor-16
Packaging
1mg
Price
$54.7
Updated
2024/03/01
Sigma-Aldrich
Product number
511075
Product name
Platelet Activating Factor-16
Packaging
5mg
Price
$125
Updated
2024/03/01
Cayman Chemical
Product number
60900
Product name
PAF C-16
Purity
≥98%
Packaging
5mg
Price
$70
Updated
2024/03/01
Cayman Chemical
Product number
60900
Product name
PAF C-16
Purity
≥98%
Packaging
10mg
Price
$120
Updated
2024/03/01
Sigma-Aldrich
Product number
P4904
Product name
β-Acetyl-γ-O-hexadecyl-L-α-phosphatidylcholine hydrate
Purity
≥98%
Packaging
1mg
Price
$58.2
Updated
2024/03/01
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Platelet Activating Factor-16 Chemical Properties,Usage,Production

Uses

PAF (C16) (cas# 74389-68-7) is a blood platelet-activating factor, used to study human airway smooth muscle cell line.

Uses

C16-02:0 PC or 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay. It may also be used to study its physicochemical properties and its interaction with peptides derived from the C-terminal domains of human apolipoprotein E.

Definition

ChEBI: A 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has hexadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis.

General Description

C16-02:0 PC, also known as 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (C16 PAF) (acetyl PAF), is a platelet-activating factor (PAF). Acetyl PAF is present in the body and it contains ether-linked hexadecyl chain at the sn-1 position and an acetyl group at the sn-2 position.

Biological Activity

Endogenous platelet-activating factor (PAF) and ligand for PAF receptors. Produced by inflammatory cells and a potent chemoattractant for polymorphonuclear neutrophils. Induces increased vascular permeability.

Biochem/physiol Actions

Platelet-activating factor (PAF) is a pro-inflammatory agent that exhibits variety of biological and pharmacological effects. It plays a major role in initiation and progression of atherosclerosis. PAF acts as a potential biomarker for coronary artery diseases. It yields LysoPAF (1-O-alkyl-2-hydroxy-sn-glycero-3-phosphocholine) on hydrolysis by platelet-activating factor-acetylhydrolase.

storage

Store at -20°C

Platelet Activating Factor-16 Preparation Products And Raw materials

Raw materials

Preparation Products

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74389-68-7, Platelet Activating Factor-16Related Search:

N-ACETYLLACTOSAMINE 1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3 phosphorylcholine 3-O-HEXADECYL-2-ACETYL-SN-GLYCERO-1-PHOSPHOCHOLINE 1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE

  • L-ALPHA-PHOSPHATIDYLCHOLINE, BETA-ACETYL-GAMMA-O-HEXADECYL
  • L-ALPHA-PHOSPHATIDYLCHOLINE, BETA-ACETYL-GAMMA-O-ALKYL
  • C16-02:0 PC
  • C16PAF
  • C16 ENANTIOMERIC PAF
  • 1-O-AKYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 1-O-PALMITYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
  • 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
  • 1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 1-O-HEXADECYL-2-ACETOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • ACGEPC
  • 3-O-HEXADECYL-2-ACETOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • PLATELET ACTIVATING FACTOR (C16)
  • PLATELET ACTIVATING FACTOR
  • PAF
  • PAF (C16)
  • 1-HEXADECYL-2-ACETYL-SN-GLYCERO-3- &
  • L-A-PHOSPHATIDYLCHOLINE, B-ACETYL-*GAMMA -O-HEXADECY
  • PAF[C16] (PLATELET ACTIVATING FACTOR [C1 6])
  • L-alpha-phosphatidylcholine-beta-acetyl-gamma-o-hexadecylhygroscopic
  • 1-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine
  • β-acetyl-γ-o-hexadecyl-l-α-phosphatidylcholine
  • 1-ALKYL-2-ACETOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • (R)-2-Acetoxy-3-(hexadecyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
  • PLATELET ACTIVATING FACTOR-16
  • 1-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine, 2-Acetyl-1-hexadecyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1-hexadecyl-2-acetyl, PAF(C16), Platelet activating factor, 1-O-Palmityl-2-acetyl-sn-glycero-3-phosphocholine monohydrate
  • Blood platelet-activating factor acether
  • C16-PAF-acether
  • PAF (C16),99%
  • PAF (C16)1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine
  • 1-hexadecyl-2-acetyl-glycero-3-phosphocholine
  • (7R)-7-(Acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium-4-oxide
  • 1-O-Palmityl-2-acetyl-sn-glycero-3-phosphocholine monohydrate
  • 2-Acetyl-1-hexadecyl-sn-glycero-3-phosphocholine
  • 3-sn-Phosphatidylcholine, 1-hexadecyl-2-acetyl
  • 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
  • 1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE;C16-02:0 PC
  • β-Acetyl-γ-O-hexadecyl-L-α-phosphatidylcholine hydrate
  • Platelet Activating Factor-16 - CAS 74389-68-7 - Calbiochem
  • Rabbit Anti-PAF antibody
  • C16-PAF(PAF (C16))
  • 74389-68-7
  • Biochemicals and Reagents
  • BioChemical
  • Phosphoglycerides
  • Glycerophosphocholines
  • Glycerides
  • Lipids