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Triamcinolone 21-acetate

Product Name
Triamcinolone 21-acetate
CAS No.
3859-65-2
Chemical Name
Triamcinolone 21-acetate
Synonyms
BNKY017-TA02;Triamcinolone 21-Acetate;Triamcinolone EP Impurity B;Triamcinolone Impurity 2 (Triamcinolone EP Impurity B);9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate;(11β,16α)-21-acetyloxy-9-fluoro-11,16,17-trihydroxypegna-1,4-diene-3,20-dione;(11β,16α)-21-acetyloxy-9-fluoro-11,16,17-trihydroxypegna-1,4-diene-3,20-dione;Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,16,17-trihydroxy-, (11β,16α)-;9-fluoro-11β,16α,17-trihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate (triamcinolone 21-acetate);2-((8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
CBNumber
CB91452896
Molecular Formula
C23H29FO7
Formula Weight
436.47
MOL File
3859-65-2.mol
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Triamcinolone 21-acetate Property

Melting point:
212-215 °C(Solv: acetone (67-64-1); ethyl ether (60-29-7))
Boiling point:
596.0±50.0 °C(Predicted)
Density 
1.38±0.1 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated, Heated)
form 
Solid
pka
11.52±0.70(Predicted)
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
T767290
Product name
Triamcinolone21-Acetate
Packaging
25mg
Price
$1320
Updated
2021/12/16
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Triamcinolone 21-acetate Chemical Properties,Usage,Production

Description

Triamcinolone 21-acetate is a synthetic anti-inflammatory drug with a triamcinolone core. It has been used for the treatment of inflammatory conditions such as arthritis and allergic disorders. The mechanism of action is unknown, but it is thought to involve the inhibition of prostaglandin synthesis by inhibiting enzymes that are involved in prostaglandin biosynthesis. Triamcinolone 21-acetate is effective against rheumatoid arthritis and other inflammatory disorders. This drug also has anti-bacterial activity, which may be due to its ability to inhibit cell membrane function or interfere with protein synthesis.

Uses

Triamcinolone 21-Acetate is an impurity of Triamcinolone (T767160), a glucocorticoid used as an antiasthmatic.

Triamcinolone 21-acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Triamcinolone 21-acetate Suppliers

3859-65-2, Triamcinolone 21-acetateRelated Search:


  • 9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate
  • Triamcinolone EP Impurity B
  • (11β,16α)-21-acetyloxy-9-fluoro-11,16,17-trihydroxypegna-1,4-diene-3,20-dione
  • BNKY017-TA02
  • Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,16,17-trihydroxy-, (11β,16α)-
  • 2-((8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
  • Triamcinolone 21-Acetate
  • (11β,16α)-21-acetyloxy-9-fluoro-11,16,17-trihydroxypegna-1,4-diene-3,20-dione
  • 9-fluoro-11β,16α,17-trihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate (triamcinolone 21-acetate)
  • 2-((8S,9R,10S,11S,13S,14S,16R,17S)-9-Fluoro-11,16,17-trihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate (Triamcinolone Impurity)
  • Triamcinolone Impurity 2 (Triamcinolone EP Impurity B)
  • 3859-65-2