2-Cyano-5-fluorobenzaldehyde
- Product Name
- 2-Cyano-5-fluorobenzaldehyde
- CAS No.
- 894779-76-1
- Chemical Name
- 2-Cyano-5-fluorobenzaldehyde
- Synonyms
- 2-Cyano-5-fluorobenzaldehyde;4-Fluoro-2-forMylbenzonitrile;Benzonitrile, 4-fluoro-2-formyl-;2-Cyano-5-fluorobenzaldehyde ISO 9001：2015 REACH
- CBNumber
- CB91456834
- Molecular Formula
- C8H4FNO
- Formula Weight
- 149.12
- MOL File
- 894779-76-1.mol
2-Cyano-5-fluorobenzaldehyde Property
- Boiling point:
- 288.0±25.0 °C(Predicted)
- Density
- 1.25±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- Light yellow to light brown Solid
Safety
- HS Code
- 2926907090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F401668
- Product name
- 4-Fluoro-2-formylbenzonitrile
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- PC905464
- Product name
- 2-Cyano-5-fluorobenzaldehyde
- Purity
- 95%
- Packaging
- 1g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- PC905464
- Product name
- 2-Cyano-5-fluorobenzaldehyde
- Purity
- 95%
- Packaging
- 5g
- Price
- $445
- Updated
- 2021/12/16
- Product number
- 4811AC
- Product name
- 4-Fluoro-2-formylbenzonitrile
- Packaging
- 10g
- Price
- $446
- Updated
- 2021/12/16
- Product number
- HCH0366263
- Product name
- 4-FLUORO-2-FORMYLBENZONITRILE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.76
- Updated
- 2021/12/16
2-Cyano-5-fluorobenzaldehyde Chemical Properties,Usage,Production
Synthesis
36282-26-5
68-12-2
894779-76-1
To an anhydrous tetrahydrofuran (THF, 20 mL) solution of 2-bromo-4-fluorobenzonitrile (5.0 g, 25.0 mmol) was slowly added isopropylmagnesium chloride (PrMgCl, 2.0 M solution of THF, 15.0 mL, 30.0 mmol) at -30 °C. The reaction temperature was maintained at -30°C with continuous stirring for 3 hours. Subsequently, N,N-dimethylformamide (DMF, 5.80 mL, 75.0 mmol) was added to the reaction system. The reaction mixture was gradually warmed to room temperature and stirring was continued for 1 hour. Upon completion of the reaction, the mixture was cooled to -10 °C, 2 M hydrochloric acid (37 mL) was slowly added and stirred at this temperature for 20 min. The reaction solution was concentrated in vacuum to 1/3 of the original volume and then extracted with ethyl acetate (EtOAc, 3 times). The organic phases were combined, dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated to give the target product 4-fluoro-2-formylbenzonitrile (3.9 g, 71% yield).
References
[1] Patent: WO2011/68821, 2011, A1. Location in patent: Page/Page column 137
2-Cyano-5-fluorobenzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Cyano-5-fluorobenzaldehyde manufacturers
- Product
- 2-Cyano-5-fluorobenzaldehyde 894779-76-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-13