2-nitro-4-Bromo-5-fluorobenzoic acid

Product Name: 2-nitro-4-Bromo-5-fluorobenzoic acid
CAS No.: 1020717-99-0
Chemical Name: 2-nitro-4-Bromo-5-fluorobenzoic acid
Synonyms: 4-Bromo-5-fL;CAS:1020717-99-0;uoro-2-nitrobenzoic acid;2-nitro-4-Bromo-5-fluorobenzoic acid;4-Bromo-5-fluoro-2-nitrobenzoicacid,98%;Benzoic acid, 4-bromo-5-fluoro-2-nitro-
CBNumber: CB91459507
Molecular Formula: C7H3BrFNO4
Formula Weight: 264.01
MOL File: 1020717-99-0.mol

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2-nitro-4-Bromo-5-fluorobenzoic acid Property

Boiling point:: 367.6±42.0 °C(Predicted)
Density: 1.967±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 1.68±0.25(Predicted)
form: crystalline powder
color: Off-white

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Safety

HS Code: 2916399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: B688693
Product name: 4-Bromo-5-fluoro-2-nitrobenzoicacid
Packaging: 250mg
Price: $55
Updated: 2021/12/16

TRC

Product number: B688693
Product name: 4-Bromo-5-fluoro-2-nitrobenzoicacid
Packaging: 500mg
Price: $65
Updated: 2021/12/16

ChemScene

Product number: CS-W012454
Product name: 4-Bromo-5-fluoro-2-nitrobenzoicacid
Purity: 99.41%
Packaging: 25g
Price: $147
Updated: 2021/12/16

Apolloscientific

Product number: PC53000
Product name: 4-Bromo-5-fluoro-2-nitrobenzoicacid
Purity: 98%
Packaging: 25g
Price: $196
Updated: 2021/12/16

Oakwood

Product number: 076482
Product name: 4-Bromo-5-fluoro-2-nitrobenzoicacid
Purity: 95+%
Packaging: 5g
Price: $130
Updated: 2021/12/16

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2-nitro-4-Bromo-5-fluorobenzoic acid Chemical Properties,Usage,Production

Uses

2-nitro-4-Bromo-5-fluorobenzoic acid is an important intermediate for the synthesis of a new generation of fluoroquinolone drugs represented by ciprofloxacin.

Synthesis

2,4-Dibromo-5-fluorotoluene was brominated with NBS, hydrolyzed in acid to form aldehyde, and then oxidized by Jones reagent to obtain 2-nitro-4-Bromo-5-fluorobenzoic acid.

References

[1] Patent: CN106146482, 2016, A. Location in patent: Paragraph 0124; 0125; 0126
[2] Patent: WO2017/98440, 2017, A1. Location in patent: Page/Page column 113
[3] Patent: WO2014/128655, 2014, A1. Location in patent: Page/Page column 20
[4] Patent: WO2015/17589, 2015, A1. Location in patent: Page/Page column 42
[5] Patent: US2015/183802, 2015, A1. Location in patent: Paragraph 1175-177

2-nitro-4-Bromo-5-fluorobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-nitro-4-Bromo-5-fluorobenzoic acid Suppliers

China 114 India 1 United Kingdom 3 United States 8 Global 126

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
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Advantage: 84

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

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Shanghai Hanhong Scientific Co.,Ltd.

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Beijing Eternalchem Co,. Ltd.

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Tianjin Jinyuda Chemical Co., Ltd.

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Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
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View Lastest Price from 2-nitro-4-Bromo-5-fluorobenzoic acid manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-nitro-4-Bromo-5-fluorobenzoic acid 1020717-99-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-11-20

Shaanxi Dideu Medichem Co. Ltd

Product: 2-nitro-4-Bromo-5-fluorobenzoic acid 1020717-99-0
Price: US $0.00-0.00/KG
Min. Order: 50mg
Purity: 99%HPLC
Supply Ability: 2000tons
Release date: 2020-01-08

Career Henan Chemical Co

Product: 2-nitro-4-Bromo-5-fluorobenzoic acid 1020717-99-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2019-07-12

1020717-99-0, 2-nitro-4-Bromo-5-fluorobenzoic acidRelated Search:

2-nitro-4-Bromo-5-fluorobenzoic acid

4-Bromo-5-fL

uoro-2-nitrobenzoic acid

Benzoic acid, 4-bromo-5-fluoro-2-nitro-

4-Bromo-5-fluoro-2-nitrobenzoicacid,98%

CAS:1020717-99-0

1020717-99-0

C7H3BrFNO4