2-bromo-4-chloro-6-nitro-phenol
- Product Name
- 2-bromo-4-chloro-6-nitro-phenol
- CAS No.
- 15969-10-5
- Chemical Name
- 2-bromo-4-chloro-6-nitro-phenol
- Synonyms
- Phloroglucinol Impurity 238;Phenol, 2-broMo-4-chloro-6-nitro-;2-?nitro-?6-?bromo-?4-?chloro-phenol
- CBNumber
- CB91466367
- Molecular Formula
- C6H3BrClNO3
- Formula Weight
- 252.45
- MOL File
- 15969-10-5.mol
2-bromo-4-chloro-6-nitro-phenol Property
- Melting point:
- 125 °C
- Boiling point:
- 250.1±35.0 °C(Predicted)
- Density
- 1.974±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Methanol (Slightly)
- pka
- 4.57±0.38(Predicted)
- form
- Solid
- color
- Yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B684523
- Product name
- 2-Bromo-4-chloro-6-nitrophenol
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B684523
- Product name
- 2-Bromo-4-chloro-6-nitrophenol
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FB159734
- Product name
- 2-Bromo-4-chloro-6-nitrophenol
- Packaging
- 1g
- Price
- $80
- Updated
- 2021/12/16
- Product number
- FB159734
- Product name
- 2-Bromo-4-chloro-6-nitrophenol
- Packaging
- 2g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- FB159734
- Product name
- 2-Bromo-4-chloro-6-nitrophenol
- Packaging
- 5G
- Price
- $200
- Updated
- 2021/12/16
2-bromo-4-chloro-6-nitro-phenol Chemical Properties,Usage,Production
Synthesis
89-64-5
15969-10-5
Step 1: 4-Chloro-2-nitrophenol (1.0 eq.) was dissolved in acetic acid (0.64 M) and cooled under ice bath conditions. Subsequently, bromine (1.1 eq.) was added slowly and dropwise to the reaction system, keeping the reaction mixture stirred in an ice bath for 3 hours, during which time it was gradually warmed up to room temperature. After completion of the reaction, bromine (0.3 eq.) was added to the system and stirring was continued for 1 hour. The progress of the reaction was monitored by thin layer chromatography (TLC) to confirm that the reaction was essentially complete. Subsequently, pre-cooled deionized water was added to the reaction mixture, which immediately produced a yellow suspension. The mixture was stirred vigorously and the precipitate was collected by filtration. The resulting yellow-orange solid was washed sequentially with deionized water and heptane to obtain a yellow powdery product. The product was dried in a high vacuum drying oven for 3 days to give 2-bromo-4-chloro-6-nitrophenol in 76% yield. The product was analyzed by liquid chromatography-mass spectrometry (LC-MS) showing (m/z) [M+H]+=291.9 and retention time (Rt)=1.45 min.
References
[1] Journal of Organic Chemistry, 2018, vol. 83, # 14, p. 7388 - 7397
[2] Patent: US2010/152160, 2010, A1. Location in patent: Page/Page column 111
[3] Patent: WO2013/49605, 2013, A1. Location in patent: Paragraph 0054
[4] Patent: WO2016/38582, 2016, A1. Location in patent: Paragraph 00335
[5] American Chemical Journal, 1904, vol. 32, p. 15
2-bromo-4-chloro-6-nitro-phenol Preparation Products And Raw materials
Raw materials
Preparation Products
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